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TransRender: a transformer-based boundary rendering segmentation network for stroke lesions

Vision transformer architectures attract widespread interest due to their robust representation capabilities of global features. Transformer-based methods as the encoder achieve superior performance compared to convolutional neural networks and other popular networks in many segmentation tasks for m...

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Autores principales: Wu, Zelin, Zhang, Xueying, Li, Fenglian, Wang, Suzhe, Li, Jiaying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601640/
https://www.ncbi.nlm.nih.gov/pubmed/37901438
http://dx.doi.org/10.3389/fnins.2023.1259677
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author Wu, Zelin
Zhang, Xueying
Li, Fenglian
Wang, Suzhe
Li, Jiaying
author_facet Wu, Zelin
Zhang, Xueying
Li, Fenglian
Wang, Suzhe
Li, Jiaying
author_sort Wu, Zelin
collection PubMed
description Vision transformer architectures attract widespread interest due to their robust representation capabilities of global features. Transformer-based methods as the encoder achieve superior performance compared to convolutional neural networks and other popular networks in many segmentation tasks for medical images. Due to the complex structure of the brain and the approximate grayscale of healthy tissue and lesions, lesion segmentation suffers from over-smooth boundaries or inaccurate segmentation. Existing methods, including the transformer, utilize stacked convolutional layers as the decoder to uniformly treat each pixel as a grid, which is convenient for feature computation. However, they often neglect the high-frequency features of the boundary and focus excessively on the region features. We propose an effective method for lesion boundary rendering called TransRender, which adaptively selects a series of important points to compute the boundary features in a point-based rendering way. The transformer-based method is selected to capture global information during the encoding stage. Several renders efficiently map the encoded features of different levels to the original spatial resolution by combining global and local features. Furthermore, the point-based function is employed to supervise the render module generating points, so that TransRender can continuously refine the uncertainty region. We conducted substantial experiments on different stroke lesion segmentation datasets to prove the efficiency of TransRender. Several evaluation metrics illustrate that our method can automatically segment the stroke lesion with relatively high accuracy and low calculation complexity.
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spelling pubmed-106016402023-10-27 TransRender: a transformer-based boundary rendering segmentation network for stroke lesions Wu, Zelin Zhang, Xueying Li, Fenglian Wang, Suzhe Li, Jiaying Front Neurosci Neuroscience Vision transformer architectures attract widespread interest due to their robust representation capabilities of global features. Transformer-based methods as the encoder achieve superior performance compared to convolutional neural networks and other popular networks in many segmentation tasks for medical images. Due to the complex structure of the brain and the approximate grayscale of healthy tissue and lesions, lesion segmentation suffers from over-smooth boundaries or inaccurate segmentation. Existing methods, including the transformer, utilize stacked convolutional layers as the decoder to uniformly treat each pixel as a grid, which is convenient for feature computation. However, they often neglect the high-frequency features of the boundary and focus excessively on the region features. We propose an effective method for lesion boundary rendering called TransRender, which adaptively selects a series of important points to compute the boundary features in a point-based rendering way. The transformer-based method is selected to capture global information during the encoding stage. Several renders efficiently map the encoded features of different levels to the original spatial resolution by combining global and local features. Furthermore, the point-based function is employed to supervise the render module generating points, so that TransRender can continuously refine the uncertainty region. We conducted substantial experiments on different stroke lesion segmentation datasets to prove the efficiency of TransRender. Several evaluation metrics illustrate that our method can automatically segment the stroke lesion with relatively high accuracy and low calculation complexity. Frontiers Media S.A. 2023-10-12 /pmc/articles/PMC10601640/ /pubmed/37901438 http://dx.doi.org/10.3389/fnins.2023.1259677 Text en Copyright © 2023 Wu, Zhang, Li, Wang and Li. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Wu, Zelin
Zhang, Xueying
Li, Fenglian
Wang, Suzhe
Li, Jiaying
TransRender: a transformer-based boundary rendering segmentation network for stroke lesions
title TransRender: a transformer-based boundary rendering segmentation network for stroke lesions
title_full TransRender: a transformer-based boundary rendering segmentation network for stroke lesions
title_fullStr TransRender: a transformer-based boundary rendering segmentation network for stroke lesions
title_full_unstemmed TransRender: a transformer-based boundary rendering segmentation network for stroke lesions
title_short TransRender: a transformer-based boundary rendering segmentation network for stroke lesions
title_sort transrender: a transformer-based boundary rendering segmentation network for stroke lesions
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601640/
https://www.ncbi.nlm.nih.gov/pubmed/37901438
http://dx.doi.org/10.3389/fnins.2023.1259677
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AT lifenglian transrenderatransformerbasedboundaryrenderingsegmentationnetworkforstrokelesions
AT wangsuzhe transrenderatransformerbasedboundaryrenderingsegmentationnetworkforstrokelesions
AT lijiaying transrenderatransformerbasedboundaryrenderingsegmentationnetworkforstrokelesions