Cargando…

Perilipin 1 Deficiency Prompts Lipolysis in Lipid Droplets and Aggravates the Pathogenesis of Persistent Immune Activation in Drosophila

Lipid droplets (LDs) are highly dynamic intracellular organelles, which are involved in lots of biological processes. However, the dynamic morphogenesis and functions of intracellular LDs during persistent innate immune responses remain obscure. In this study, we induce long-term systemic immune act...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Lei, Lin, Jiaxin, Yang, Kaiyan, Wang, Weina, Lv, Yan, Zeng, Xiangkang, Zhao, Yaya, Yu, Junjing, Pan, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	S. Karger AG 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601664/ https://www.ncbi.nlm.nih.gov/pubmed/37742619 http://dx.doi.org/10.1159/000534099

Ejemplares similares

Adipocyte lipolysis affects Perilipin 5 and cristae organization at the cardiac lipid droplet-mitochondrial interface
por: Varghese, Mita, et al.
Publicado: (2019)

Pik3r1 Is Required for Glucocorticoid-Induced Perilipin 1 Phosphorylation in Lipid Droplet for Adipocyte Lipolysis
por: Kuo, Taiyi, et al.
Publicado: (2017)

Shrimp Lipid Droplet Protein Perilipin Involves in the Pathogenesis of AHPND-Causing Vibrio parahaemolyticus
por: Wang, Chuanqi, et al.
Publicado: (2022)

Nuclear Perilipin 5 integrates lipid droplet lipolysis with PGC-1α/SIRT1-dependent transcriptional regulation of mitochondrial function
por: Gallardo-Montejano, Violeta I., et al.
Publicado: (2016)

Imaging cytoplasmic lipid droplets in vivo with fluorescent perilipin 2 and perilipin 3 knock-in zebrafish
por: Wilson, Meredith H, et al.
Publicado: (2021)

Caffeic Acid Phenethyl Ester Inhibits Basal Lipolysis by Activating PPAR-Gamma and Increasing Lipid Droplet-Associated Perilipin in Mature Rat Adipocytes
por: Trang, Nguyen Thi Thu, et al.
Publicado: (2022)

BAP31 depletion inhibited adipogenesis, repressed lipolysis and promoted lipid droplets abnormal growth via attenuating Perilipin1 proteasomal degradation
por: Wei, Xueying, et al.
Publicado: (2023)

Correction: Imaging cytoplasmic lipid droplets in vivo with fluorescent perilipin 2 and perilipin 3 knock-in zebrafish
por: Wilson, Meredith H, et al.
Publicado: (2023)

Muscle Lipid Metabolism: Role of Lipid Droplets and Perilipins
por: Morales, Pablo Esteban, et al.
Publicado: (2017)

Perilipins: a diversity of intracellular lipid droplet proteins
por: Itabe, Hiroyuki, et al.
Publicado: (2017)

Amidation-Modified Apelin-13 Regulates PPARγ and Perilipin to Inhibit Adipogenic Differentiation and Promote Lipolysis
por: Wang, Sha, et al.
Publicado: (2021)

Perilipin2 plays a positive role in adipocytes during lipolysis by escaping proteasomal degradation
por: Takahashi, Yu, et al.
Publicado: (2016)

PNPLA3(I148M) Inhibits Lipolysis by Perilipin-5-Dependent Competition with ATGL
por: Witzel, Hagen Roland, et al.
Publicado: (2022)

Perilipin 1 moves between the fat droplet and the endoplasmic reticulum
por: Skinner, James R., et al.
Publicado: (2013)

Expression of perilipin 5 promotes lipid droplet formation in yeast
por: Mishra, Shirish, et al.
Publicado: (2015)

Sar1 Affects the Localization of Perilipin 2 to Lipid Droplets
por: Makiyama, Tomohiko, et al.
Publicado: (2022)

Microbiota aggravates the pathogenesis of Drosophila acutely exposed to vehicle exhaust
por: Li, Yujuan, et al.
Publicado: (2022)

Lipid Droplets, Perilipins and Cytokeratins – Unravelled Liaisons in Epithelium-Derived Cells
por: Heid, Hans, et al.
Publicado: (2013)

On the Formation of Lipid Droplets in Human Adipocytes: The Organization of the Perilipin–Vimentin Cortex
por: Heid, Hans, et al.
Publicado: (2014)

Differential Phosphorylation of Perilipin 1A at the Initiation of Lipolysis Revealed by Novel Monoclonal Antibodies and High Content Analysis
por: McDonough, Patrick M., et al.
Publicado: (2013)

Low cardiac lipolysis reduces mitochondrial fission and prevents lipotoxic heart dysfunction in Perilipin 5 mutant mice
por: Kolleritsch, Stephanie, et al.
Publicado: (2020)

Perilipin 5 deficiency aggravates cardiac hypertrophy by stimulating lactate production in leptin-deficient mice
por: Jian, Lele, et al.
Publicado: (2023)

The lipid droplet coat protein perilipin 5 also localizes to muscle mitochondria
por: Bosma, Madeleen, et al.
Publicado: (2011)

Conserved Amphipathic Helices Mediate Lipid Droplet Targeting of Perilipins 1–3
por: Rowe, Emily R., et al.
Publicado: (2016)

Corrigendum to: Low cardiac lipolysis reduces mitochondrial fission and prevents lipotoxic heart dysfunction in Perilipin 5 mutant mice
Publicado: (2019)

A giant amphipathic helix from a perilipin that is adapted for coating lipid droplets
por: Čopič, Alenka, et al.
Publicado: (2018)

Pet10p is a yeast perilipin that stabilizes lipid droplets and promotes their assembly
por: Gao, Qiang, et al.
Publicado: (2017)

Dual binding motifs underpin the hierarchical association of perilipins1–3 with lipid droplets
por: Ajjaji, Dalila, et al.
Publicado: (2019)

Lipid droplet biology and evolution illuminated by the characterization of a novel perilipin in teleost fish
por: Granneman, James G, et al.
Publicado: (2017)

Correction: Conserved amphipathic helices mediate lipid droplet targeting of perilipins 1–3
por: Rowe, Emily R., et al.
Publicado: (2021)

Bilayer-Embedded Lipid Droplets Coated with Perilipin-2 Display a Pancake Shape
por: Puza, Sevde, et al.
Publicado: (2023)

Challenges in Pharmacological Intervention in Perilipins (PLINs) to Modulate Lipid Droplet Dynamics in Obesity and Cancer
por: Bombarda-Rocha, Victória, et al.
Publicado: (2023)

Remodeling of Lipid Droplets during Lipolysis and Growth in Adipocytes
por: Paar, Margret, et al.
Publicado: (2012)

Novel Effect of p-Coumaric Acid on Hepatic Lipolysis: Inhibition of Hepatic Lipid-Droplets
por: Yuan, Zhiyi, et al.
Publicado: (2023)

Okadaic Acid, a Bioactive Fatty Acid from Halichondria okadai, Stimulates Lipolysis in Rat Adipocytes: The Pivotal Role of Perilipin Translocation
por: Chang, Nen-Chung, et al.
Publicado: (2013)

Perilipin1 promotes unilocular lipid droplet formation through the activation of Fsp27 in adipocytes
por: Sun, Zhiqi, et al.
Publicado: (2013)

Perilipin 3 promotes the formation of membrane domains enriched in diacylglycerol and lipid droplet biogenesis proteins
por: Khaddaj, Rasha, et al.
Publicado: (2023)

Lipid droplet size directs lipolysis and lipophagy catabolism in hepatocytes
por: Schott, Micah B., et al.
Publicado: (2019)

Mitotane Targets Lipid Droplets to Induce Lipolysis in Adrenocortical Carcinoma
por: Warde, Kate M, et al.
Publicado: (2022)

Adoption of PERILIPIN as a unifying nomenclature for the mammalian PAT-family of intracellular lipid storage droplet proteins
por: Kimmel, Alan R., et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_rbumtpaunqdotqnthjojp0tfk5