Effective Management of Nasal Vestibule Squamous Cell Carcinoma with Cemiplimab: A Case Report

Nasal vestibule squamous cell carcinoma (SCC) is a rare malignancy with limited treatment options. This case report presents an 83-year-old female with SCC of the nasal vestibule who was ineligible for surgery or radiotherapy due to various factors. The patient was successfully treated with cemiplim...

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Autores principales: Costabile, Ferdinando, Donnarumma, Marianna, Piscosquito, Arianna, Ingenito, Concetta, Iuliucci, Michela Rosaria, Buonerba, Carlo, Di Lorenzo, Giuseppe, Di Trolio, Rossella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601738/
https://www.ncbi.nlm.nih.gov/pubmed/37900804
http://dx.doi.org/10.1159/000531843
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author Costabile, Ferdinando
Donnarumma, Marianna
Piscosquito, Arianna
Ingenito, Concetta
Iuliucci, Michela Rosaria
Buonerba, Carlo
Di Lorenzo, Giuseppe
Di Trolio, Rossella
author_facet Costabile, Ferdinando
Donnarumma, Marianna
Piscosquito, Arianna
Ingenito, Concetta
Iuliucci, Michela Rosaria
Buonerba, Carlo
Di Lorenzo, Giuseppe
Di Trolio, Rossella
author_sort Costabile, Ferdinando
collection PubMed
description Nasal vestibule squamous cell carcinoma (SCC) is a rare malignancy with limited treatment options. This case report presents an 83-year-old female with SCC of the nasal vestibule who was ineligible for surgery or radiotherapy due to various factors. The patient was successfully treated with cemiplimab, a systemic anti-PD-1 antibody, resulting in a remarkable tumor reduction without any observed side effects. This is the first reported case of nasal vestibule SCC treated with cemiplimab, highlighting its potential as a promising therapeutic option.
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spelling pubmed-106017382023-10-27 Effective Management of Nasal Vestibule Squamous Cell Carcinoma with Cemiplimab: A Case Report Costabile, Ferdinando Donnarumma, Marianna Piscosquito, Arianna Ingenito, Concetta Iuliucci, Michela Rosaria Buonerba, Carlo Di Lorenzo, Giuseppe Di Trolio, Rossella Case Rep Oncol Case Report Nasal vestibule squamous cell carcinoma (SCC) is a rare malignancy with limited treatment options. This case report presents an 83-year-old female with SCC of the nasal vestibule who was ineligible for surgery or radiotherapy due to various factors. The patient was successfully treated with cemiplimab, a systemic anti-PD-1 antibody, resulting in a remarkable tumor reduction without any observed side effects. This is the first reported case of nasal vestibule SCC treated with cemiplimab, highlighting its potential as a promising therapeutic option. S. Karger AG 2023-09-19 /pmc/articles/PMC10601738/ /pubmed/37900804 http://dx.doi.org/10.1159/000531843 Text en © 2023 The Author(s). Published by S. Karger AG, Basel https://creativecommons.org/licenses/by-nc/4.0/This article is licensed under the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Case Report
Costabile, Ferdinando
Donnarumma, Marianna
Piscosquito, Arianna
Ingenito, Concetta
Iuliucci, Michela Rosaria
Buonerba, Carlo
Di Lorenzo, Giuseppe
Di Trolio, Rossella
Effective Management of Nasal Vestibule Squamous Cell Carcinoma with Cemiplimab: A Case Report
title Effective Management of Nasal Vestibule Squamous Cell Carcinoma with Cemiplimab: A Case Report
title_full Effective Management of Nasal Vestibule Squamous Cell Carcinoma with Cemiplimab: A Case Report
title_fullStr Effective Management of Nasal Vestibule Squamous Cell Carcinoma with Cemiplimab: A Case Report
title_full_unstemmed Effective Management of Nasal Vestibule Squamous Cell Carcinoma with Cemiplimab: A Case Report
title_short Effective Management of Nasal Vestibule Squamous Cell Carcinoma with Cemiplimab: A Case Report
title_sort effective management of nasal vestibule squamous cell carcinoma with cemiplimab: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601738/
https://www.ncbi.nlm.nih.gov/pubmed/37900804
http://dx.doi.org/10.1159/000531843
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