Pembrolizumab-Induced Rhabdomyolysis in a Clear Cell Renal Cell Carcinoma Patient: A Case Report

Pembrolizumab is one of the approved treatments for many types of cancer including clear cell renal cell carcinoma (ccRCC). It has improved the prognosis of renal cell carcinoma, yet has many possible immune-related side effects. We discuss a rare case of rhabdomyolysis in an ccRCC patient treated w...

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Detalles Bibliográficos
Autores principales: Altermanini, Mohammad, Ali, Khaled, Alwassiti, Wisam, Almohtasib, Suliman, Omar, Nabil E., Zafar, Abdulaziz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601742/
https://www.ncbi.nlm.nih.gov/pubmed/37900826
http://dx.doi.org/10.1159/000532100
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author Altermanini, Mohammad
Ali, Khaled
Alwassiti, Wisam
Almohtasib, Suliman
Omar, Nabil E.
Zafar, Abdulaziz
author_facet Altermanini, Mohammad
Ali, Khaled
Alwassiti, Wisam
Almohtasib, Suliman
Omar, Nabil E.
Zafar, Abdulaziz
author_sort Altermanini, Mohammad
collection PubMed
description Pembrolizumab is one of the approved treatments for many types of cancer including clear cell renal cell carcinoma (ccRCC). It has improved the prognosis of renal cell carcinoma, yet has many possible immune-related side effects. We discuss a rare case of rhabdomyolysis in an ccRCC patient treated with pembrolizumab. The case was complicated with acute kidney injury and severe hypothyroidism, which can be attributed to pembrolizumab.
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spelling pubmed-106017422023-10-27 Pembrolizumab-Induced Rhabdomyolysis in a Clear Cell Renal Cell Carcinoma Patient: A Case Report Altermanini, Mohammad Ali, Khaled Alwassiti, Wisam Almohtasib, Suliman Omar, Nabil E. Zafar, Abdulaziz Case Rep Oncol Case Report Pembrolizumab is one of the approved treatments for many types of cancer including clear cell renal cell carcinoma (ccRCC). It has improved the prognosis of renal cell carcinoma, yet has many possible immune-related side effects. We discuss a rare case of rhabdomyolysis in an ccRCC patient treated with pembrolizumab. The case was complicated with acute kidney injury and severe hypothyroidism, which can be attributed to pembrolizumab. S. Karger AG 2023-08-25 /pmc/articles/PMC10601742/ /pubmed/37900826 http://dx.doi.org/10.1159/000532100 Text en © 2023 The Author(s). Published by S. Karger AG, Basel https://creativecommons.org/licenses/by-nc/4.0/This article is licensed under the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Case Report
Altermanini, Mohammad
Ali, Khaled
Alwassiti, Wisam
Almohtasib, Suliman
Omar, Nabil E.
Zafar, Abdulaziz
Pembrolizumab-Induced Rhabdomyolysis in a Clear Cell Renal Cell Carcinoma Patient: A Case Report
title Pembrolizumab-Induced Rhabdomyolysis in a Clear Cell Renal Cell Carcinoma Patient: A Case Report
title_full Pembrolizumab-Induced Rhabdomyolysis in a Clear Cell Renal Cell Carcinoma Patient: A Case Report
title_fullStr Pembrolizumab-Induced Rhabdomyolysis in a Clear Cell Renal Cell Carcinoma Patient: A Case Report
title_full_unstemmed Pembrolizumab-Induced Rhabdomyolysis in a Clear Cell Renal Cell Carcinoma Patient: A Case Report
title_short Pembrolizumab-Induced Rhabdomyolysis in a Clear Cell Renal Cell Carcinoma Patient: A Case Report
title_sort pembrolizumab-induced rhabdomyolysis in a clear cell renal cell carcinoma patient: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601742/
https://www.ncbi.nlm.nih.gov/pubmed/37900826
http://dx.doi.org/10.1159/000532100
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