Cargando…
Navigating Complexities in Pediatric Rhabdomyosarcoma: A Case Report on Its Neurological Implications
This case report presents a 12-year-old male with a rare manifestation of rhabdomyosarcoma (RMS), emphasizing diagnostic and therapeutic challenges. The patient exhibited firm, tender facial swelling and underwent diagnostic procedures including imaging and biopsy, confirming RMS. Treatment involved...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601752/ https://www.ncbi.nlm.nih.gov/pubmed/37900538 http://dx.doi.org/10.7759/cureus.45991 |
_version_ | 1785126257737859072 |
---|---|
author | Haider, Anum Sunkara, Vyshnavidevi Basnet, Sagarika Affaf, Maryam Ekhator, Chukwuyem |
author_facet | Haider, Anum Sunkara, Vyshnavidevi Basnet, Sagarika Affaf, Maryam Ekhator, Chukwuyem |
author_sort | Haider, Anum |
collection | PubMed |
description | This case report presents a 12-year-old male with a rare manifestation of rhabdomyosarcoma (RMS), emphasizing diagnostic and therapeutic challenges. The patient exhibited firm, tender facial swelling and underwent diagnostic procedures including imaging and biopsy, confirming RMS. Treatment involved a multi-agent chemotherapy regimen and radiotherapy, leading to a significant tumor reduction. However, neurological deficits emerged one month after treatment, suggesting neural invasion. The case highlights the need for vigilant monitoring and a multimodal treatment approach in managing RMS. It also raises questions about neural invasion risks post-treatment, contributing valuable insights to existing literature and advocating for further research in this rare pediatric cancer. |
format | Online Article Text |
id | pubmed-10601752 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-106017522023-10-27 Navigating Complexities in Pediatric Rhabdomyosarcoma: A Case Report on Its Neurological Implications Haider, Anum Sunkara, Vyshnavidevi Basnet, Sagarika Affaf, Maryam Ekhator, Chukwuyem Cureus Pediatrics This case report presents a 12-year-old male with a rare manifestation of rhabdomyosarcoma (RMS), emphasizing diagnostic and therapeutic challenges. The patient exhibited firm, tender facial swelling and underwent diagnostic procedures including imaging and biopsy, confirming RMS. Treatment involved a multi-agent chemotherapy regimen and radiotherapy, leading to a significant tumor reduction. However, neurological deficits emerged one month after treatment, suggesting neural invasion. The case highlights the need for vigilant monitoring and a multimodal treatment approach in managing RMS. It also raises questions about neural invasion risks post-treatment, contributing valuable insights to existing literature and advocating for further research in this rare pediatric cancer. Cureus 2023-09-26 /pmc/articles/PMC10601752/ /pubmed/37900538 http://dx.doi.org/10.7759/cureus.45991 Text en Copyright © 2023, Haider et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Pediatrics Haider, Anum Sunkara, Vyshnavidevi Basnet, Sagarika Affaf, Maryam Ekhator, Chukwuyem Navigating Complexities in Pediatric Rhabdomyosarcoma: A Case Report on Its Neurological Implications |
title | Navigating Complexities in Pediatric Rhabdomyosarcoma: A Case Report on Its Neurological Implications |
title_full | Navigating Complexities in Pediatric Rhabdomyosarcoma: A Case Report on Its Neurological Implications |
title_fullStr | Navigating Complexities in Pediatric Rhabdomyosarcoma: A Case Report on Its Neurological Implications |
title_full_unstemmed | Navigating Complexities in Pediatric Rhabdomyosarcoma: A Case Report on Its Neurological Implications |
title_short | Navigating Complexities in Pediatric Rhabdomyosarcoma: A Case Report on Its Neurological Implications |
title_sort | navigating complexities in pediatric rhabdomyosarcoma: a case report on its neurological implications |
topic | Pediatrics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601752/ https://www.ncbi.nlm.nih.gov/pubmed/37900538 http://dx.doi.org/10.7759/cureus.45991 |
work_keys_str_mv | AT haideranum navigatingcomplexitiesinpediatricrhabdomyosarcomaacasereportonitsneurologicalimplications AT sunkaravyshnavidevi navigatingcomplexitiesinpediatricrhabdomyosarcomaacasereportonitsneurologicalimplications AT basnetsagarika navigatingcomplexitiesinpediatricrhabdomyosarcomaacasereportonitsneurologicalimplications AT affafmaryam navigatingcomplexitiesinpediatricrhabdomyosarcomaacasereportonitsneurologicalimplications AT ekhatorchukwuyem navigatingcomplexitiesinpediatricrhabdomyosarcomaacasereportonitsneurologicalimplications |