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Navigating Complexities in Pediatric Rhabdomyosarcoma: A Case Report on Its Neurological Implications

This case report presents a 12-year-old male with a rare manifestation of rhabdomyosarcoma (RMS), emphasizing diagnostic and therapeutic challenges. The patient exhibited firm, tender facial swelling and underwent diagnostic procedures including imaging and biopsy, confirming RMS. Treatment involved...

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Autores principales: Haider, Anum, Sunkara, Vyshnavidevi, Basnet, Sagarika, Affaf, Maryam, Ekhator, Chukwuyem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601752/
https://www.ncbi.nlm.nih.gov/pubmed/37900538
http://dx.doi.org/10.7759/cureus.45991
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author Haider, Anum
Sunkara, Vyshnavidevi
Basnet, Sagarika
Affaf, Maryam
Ekhator, Chukwuyem
author_facet Haider, Anum
Sunkara, Vyshnavidevi
Basnet, Sagarika
Affaf, Maryam
Ekhator, Chukwuyem
author_sort Haider, Anum
collection PubMed
description This case report presents a 12-year-old male with a rare manifestation of rhabdomyosarcoma (RMS), emphasizing diagnostic and therapeutic challenges. The patient exhibited firm, tender facial swelling and underwent diagnostic procedures including imaging and biopsy, confirming RMS. Treatment involved a multi-agent chemotherapy regimen and radiotherapy, leading to a significant tumor reduction. However, neurological deficits emerged one month after treatment, suggesting neural invasion. The case highlights the need for vigilant monitoring and a multimodal treatment approach in managing RMS. It also raises questions about neural invasion risks post-treatment, contributing valuable insights to existing literature and advocating for further research in this rare pediatric cancer.
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spelling pubmed-106017522023-10-27 Navigating Complexities in Pediatric Rhabdomyosarcoma: A Case Report on Its Neurological Implications Haider, Anum Sunkara, Vyshnavidevi Basnet, Sagarika Affaf, Maryam Ekhator, Chukwuyem Cureus Pediatrics This case report presents a 12-year-old male with a rare manifestation of rhabdomyosarcoma (RMS), emphasizing diagnostic and therapeutic challenges. The patient exhibited firm, tender facial swelling and underwent diagnostic procedures including imaging and biopsy, confirming RMS. Treatment involved a multi-agent chemotherapy regimen and radiotherapy, leading to a significant tumor reduction. However, neurological deficits emerged one month after treatment, suggesting neural invasion. The case highlights the need for vigilant monitoring and a multimodal treatment approach in managing RMS. It also raises questions about neural invasion risks post-treatment, contributing valuable insights to existing literature and advocating for further research in this rare pediatric cancer. Cureus 2023-09-26 /pmc/articles/PMC10601752/ /pubmed/37900538 http://dx.doi.org/10.7759/cureus.45991 Text en Copyright © 2023, Haider et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pediatrics
Haider, Anum
Sunkara, Vyshnavidevi
Basnet, Sagarika
Affaf, Maryam
Ekhator, Chukwuyem
Navigating Complexities in Pediatric Rhabdomyosarcoma: A Case Report on Its Neurological Implications
title Navigating Complexities in Pediatric Rhabdomyosarcoma: A Case Report on Its Neurological Implications
title_full Navigating Complexities in Pediatric Rhabdomyosarcoma: A Case Report on Its Neurological Implications
title_fullStr Navigating Complexities in Pediatric Rhabdomyosarcoma: A Case Report on Its Neurological Implications
title_full_unstemmed Navigating Complexities in Pediatric Rhabdomyosarcoma: A Case Report on Its Neurological Implications
title_short Navigating Complexities in Pediatric Rhabdomyosarcoma: A Case Report on Its Neurological Implications
title_sort navigating complexities in pediatric rhabdomyosarcoma: a case report on its neurological implications
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601752/
https://www.ncbi.nlm.nih.gov/pubmed/37900538
http://dx.doi.org/10.7759/cureus.45991
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