Optic Neuritis following Second Administration of COVID-19 Vaccine: A Case Report

A 28-year-old woman presented to eye casualty with signs and symptoms suggestive of optic neuritis following a recent COVID-19 vaccination (the Moderna mRNA-1273 vaccine). The best corrected visual acuity was 6/15 in the right eye and 6/6 in the left eye with a relative afferent pupillary defect in...

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Autores principales: Saxton, Edward, Panchasara, Binita, Sarangapani, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601799/
https://www.ncbi.nlm.nih.gov/pubmed/37901633
http://dx.doi.org/10.1159/000531526
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author Saxton, Edward
Panchasara, Binita
Sarangapani, Susan
author_facet Saxton, Edward
Panchasara, Binita
Sarangapani, Susan
author_sort Saxton, Edward
collection PubMed
description A 28-year-old woman presented to eye casualty with signs and symptoms suggestive of optic neuritis following a recent COVID-19 vaccination (the Moderna mRNA-1273 vaccine). The best corrected visual acuity was 6/15 in the right eye and 6/6 in the left eye with a relative afferent pupillary defect in the right eye. Following examination and investigation, she was found to fit the McDonald criteria for multiple sclerosis and was commenced on disease-modifying therapy. Demyelinating events have been identified to occur following COVID-19 vaccinations. In this case, we have found that the Moderna mRNA-1273 vaccine could have contributed to the development of optic neuritis following a second dose of the vaccine.
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spelling pubmed-106017992023-10-27 Optic Neuritis following Second Administration of COVID-19 Vaccine: A Case Report Saxton, Edward Panchasara, Binita Sarangapani, Susan Case Rep Ophthalmol Case Report A 28-year-old woman presented to eye casualty with signs and symptoms suggestive of optic neuritis following a recent COVID-19 vaccination (the Moderna mRNA-1273 vaccine). The best corrected visual acuity was 6/15 in the right eye and 6/6 in the left eye with a relative afferent pupillary defect in the right eye. Following examination and investigation, she was found to fit the McDonald criteria for multiple sclerosis and was commenced on disease-modifying therapy. Demyelinating events have been identified to occur following COVID-19 vaccinations. In this case, we have found that the Moderna mRNA-1273 vaccine could have contributed to the development of optic neuritis following a second dose of the vaccine. S. Karger AG 2023-08-23 /pmc/articles/PMC10601799/ /pubmed/37901633 http://dx.doi.org/10.1159/000531526 Text en © 2023 The Author(s). Published by S. Karger AG, Basel https://creativecommons.org/licenses/by-nc/4.0/This article is licensed under the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Case Report
Saxton, Edward
Panchasara, Binita
Sarangapani, Susan
Optic Neuritis following Second Administration of COVID-19 Vaccine: A Case Report
title Optic Neuritis following Second Administration of COVID-19 Vaccine: A Case Report
title_full Optic Neuritis following Second Administration of COVID-19 Vaccine: A Case Report
title_fullStr Optic Neuritis following Second Administration of COVID-19 Vaccine: A Case Report
title_full_unstemmed Optic Neuritis following Second Administration of COVID-19 Vaccine: A Case Report
title_short Optic Neuritis following Second Administration of COVID-19 Vaccine: A Case Report
title_sort optic neuritis following second administration of covid-19 vaccine: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601799/
https://www.ncbi.nlm.nih.gov/pubmed/37901633
http://dx.doi.org/10.1159/000531526
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