PSGL-1 Blockade Induces Classical Activation of Human Tumor-associated Macrophages

The immune suppressive microenvironment is a major culprit for difficult-to-treat solid cancers. Particularly, inhibitory tumor-associated macrophages (TAM) define the resistant nature of the tumor milieu. To define tumor-enabling mechanisms of TAMs, we analyzed molecular clinical datasets correlati...

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Detalles Bibliográficos
Autores principales: Kauffman, Kevin, Manfra, Denise, Nowakowska, Dominika, Zafari, Mohammad, Nguyen, Phuong A., Phennicie, Ryan, Vollmann, Elisabeth H., O'Nuallain, Brian, Basinski, Sara, Komoroski, Veronica, Rooney, Kate, Culyba, Elizabeth K., Wahle, Joseph, Ries, Carola, Brehm, Michael, Sazinsky, Steve, Feldman, Igor, Novobrantseva, Tatiana I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601817/
https://www.ncbi.nlm.nih.gov/pubmed/37819238
http://dx.doi.org/10.1158/2767-9764.CRC-22-0513

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601817/
https://www.ncbi.nlm.nih.gov/pubmed/37819238
http://dx.doi.org/10.1158/2767-9764.CRC-22-0513

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