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Delayed Bacterial Endotheliitis and Endophthalmitis 11 Years after Cataract Surgery

Infective endophthalmitis is an uncommon complication following intraocular surgery. Chronic endophthalmitis may present some time after intraocular surgery, making the diagnosis challenging. Cutibacterium acnes is a well-recognised causative agent of these chronic infections. Practitioners should b...

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Autores principales: Poon, Elisabeth, Poon, Alexander, McKelvie, Penelope, Levitz, Lewis, Zamir, Ehud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601837/
https://www.ncbi.nlm.nih.gov/pubmed/37901637
http://dx.doi.org/10.1159/000531501
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author Poon, Elisabeth
Poon, Alexander
McKelvie, Penelope
Levitz, Lewis
Zamir, Ehud
author_facet Poon, Elisabeth
Poon, Alexander
McKelvie, Penelope
Levitz, Lewis
Zamir, Ehud
author_sort Poon, Elisabeth
collection PubMed
description Infective endophthalmitis is an uncommon complication following intraocular surgery. Chronic endophthalmitis may present some time after intraocular surgery, making the diagnosis challenging. Cutibacterium acnes is a well-recognised causative agent of these chronic infections. Practitioners should be aware of the conditions required to culture this slow-growing organism. We report a case of delayed low-grade endophthalmitis presenting 11 years after cataract surgery. Cutibacterium acnes and Staphylococcus warneri were cultured from Descemet’s membrane biopsy following three failed previous attempts at microbiological studies. Clinical features of the infection included discrete white granules on the iris, endothelium, and within the capsular bag of the patient’s right eye. The patient presented with no signs of systemic infection and the left eye was normal on examination. Bullous keratopathy, secondary to endothelial dysfunction was a feature of this infection. This retrospective case report illustrates the prolonged periods for which Cutibacterium acnes can remain latent before causing clinical signs. While uncommon, endothelial involvement may occur and clinicians should consider low-grade infective endophthalmitis in cases with corneal oedema.
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spelling pubmed-106018372023-10-27 Delayed Bacterial Endotheliitis and Endophthalmitis 11 Years after Cataract Surgery Poon, Elisabeth Poon, Alexander McKelvie, Penelope Levitz, Lewis Zamir, Ehud Case Rep Ophthalmol Case Report Infective endophthalmitis is an uncommon complication following intraocular surgery. Chronic endophthalmitis may present some time after intraocular surgery, making the diagnosis challenging. Cutibacterium acnes is a well-recognised causative agent of these chronic infections. Practitioners should be aware of the conditions required to culture this slow-growing organism. We report a case of delayed low-grade endophthalmitis presenting 11 years after cataract surgery. Cutibacterium acnes and Staphylococcus warneri were cultured from Descemet’s membrane biopsy following three failed previous attempts at microbiological studies. Clinical features of the infection included discrete white granules on the iris, endothelium, and within the capsular bag of the patient’s right eye. The patient presented with no signs of systemic infection and the left eye was normal on examination. Bullous keratopathy, secondary to endothelial dysfunction was a feature of this infection. This retrospective case report illustrates the prolonged periods for which Cutibacterium acnes can remain latent before causing clinical signs. While uncommon, endothelial involvement may occur and clinicians should consider low-grade infective endophthalmitis in cases with corneal oedema. S. Karger AG 2023-08-16 /pmc/articles/PMC10601837/ /pubmed/37901637 http://dx.doi.org/10.1159/000531501 Text en © 2023 The Author(s). Published by S. Karger AG, Basel https://creativecommons.org/licenses/by-nc/4.0/This article is licensed under the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Case Report
Poon, Elisabeth
Poon, Alexander
McKelvie, Penelope
Levitz, Lewis
Zamir, Ehud
Delayed Bacterial Endotheliitis and Endophthalmitis 11 Years after Cataract Surgery
title Delayed Bacterial Endotheliitis and Endophthalmitis 11 Years after Cataract Surgery
title_full Delayed Bacterial Endotheliitis and Endophthalmitis 11 Years after Cataract Surgery
title_fullStr Delayed Bacterial Endotheliitis and Endophthalmitis 11 Years after Cataract Surgery
title_full_unstemmed Delayed Bacterial Endotheliitis and Endophthalmitis 11 Years after Cataract Surgery
title_short Delayed Bacterial Endotheliitis and Endophthalmitis 11 Years after Cataract Surgery
title_sort delayed bacterial endotheliitis and endophthalmitis 11 years after cataract surgery
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601837/
https://www.ncbi.nlm.nih.gov/pubmed/37901637
http://dx.doi.org/10.1159/000531501
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