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The roles of JAK2/STAT3 signaling in fusion of the secondary palate

Cleft palate has a multifactorial etiology. In palatal fusion, the contacting medial edge epithelium (MEE) forms the epithelial seam, which is subsequently removed with the reduction of p63. Failure in this process results in a cleft palate. We herein report the involvement of janus kinase 2 (JAK2)/...

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Detalles Bibliográficos
Autores principales: Yoshida, Naoki, Inubushi, Toshihiro, Hirose, Takumi, Aoyama, Gozo, Kurosaka, Hiroshi, Yamashiro, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602007/
https://www.ncbi.nlm.nih.gov/pubmed/37846594
http://dx.doi.org/10.1242/dmm.050085