Increase in brain glycogen levels ameliorates Huntington's disease phenotype and rescues neurodegeneration in Drosophila

Under normal physiological conditions, the mammalian brain contains very little glycogen, most of which is stored in astrocytes. However, the aging brain and the subareas of the brain in patients with neurodegenerative disorders tend to accumulate glycogen, the cause and significance of which remain...

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Detalles Bibliográficos
Autores principales: Onkar, Akanksha, Sheshadri, Deepashree, Rai, Anupama, Gupta, Arjit Kant, Gupta, Nitin, Ganesh, Subramaniam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602008/
https://www.ncbi.nlm.nih.gov/pubmed/37681238
http://dx.doi.org/10.1242/dmm.050238

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602008/
https://www.ncbi.nlm.nih.gov/pubmed/37681238
http://dx.doi.org/10.1242/dmm.050238

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