Direct ionic stress sensing and mitigation by the transcription factor NFAT5

Homeostatic control of intracellular ionic strength is essential for protein, organelle and genome function, yet mechanisms that sense and enable adaptation to ionic stress remain poorly understood in animals. We find that the transcription factor NFAT5 directly senses solution ionic strength using...

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Detalles Bibliográficos
Autores principales: Khandwala, Chandni B., Sarkar, Parijat, Schmidt, H. Broder, Ma, Mengxiao, Kinnebrew, Maia, Pusapati, Ganesh V., Patel, Bhaven B., Tillo, Desiree, Lebensohn, Andres M., Rohatgi, Rajat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602047/
https://www.ncbi.nlm.nih.gov/pubmed/37886503
http://dx.doi.org/10.1101/2023.09.23.559074

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