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Interferon induced circRNAs escape herpesvirus host shutoff and suppress lytic infection

A first line of defense during infection is expression of interferon (IFN)-stimulated gene products which suppress viral lytic infection. To combat this, herpesviruses express endoribonucleases to deplete host RNAs. Here we demonstrate that IFN-induced circular RNAs (circRNAs) can escape viral-media...

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Detalles Bibliográficos
Autores principales: Dremel, Sarah E., Tagawa, Takanobu, Koparde, Vishal N., Arbuckle, Jesse H., Kristie, Thomas M., Krug, Laurie T., Ziegelbauer, Joseph M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602050/
https://www.ncbi.nlm.nih.gov/pubmed/37886542
http://dx.doi.org/10.1101/2023.09.07.556698