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Power, measurement error, and pleiotropy robustness in twin-design extensions to Mendelian Randomization

Mendelian Randomization (MR) has become an important tool for causal inference in the health sciences. It takes advantage of the random segregation of alleles to control for background confounding factors. In brief, the method works by using genetic variants as instrumental variables, but it depends...

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Detalles Bibliográficos
Autores principales:	Castro-de-Araujo, Luis FS, Singh, Madhurbain, Zhou, Yi, Vinh, Philip, Maes, Hermine HM, Verhulst, Brad, Dolan, Conor V, Neale, Michael C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Journal Experts 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602165/ https://www.ncbi.nlm.nih.gov/pubmed/37886585 http://dx.doi.org/10.21203/rs.3.rs-3411642/v1

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