Heterogeneous genetic architectures and evolutionary genomics of prostate cancer in Sub-Saharan Africa

Men of African descent have the highest prostate cancer (CaP) incidence and mortality rates, yet the genetic basis of CaP in African men has been understudied. We used genomic data from 3,963 CaP cases and 3,509 controls recruited in Ghana, Nigeria, Senegal, South Africa, and Uganda, to infer ancest...

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Autores principales: Rebbeck, Timothy, Janivara, Rohini, Chen, Wenlong, Hazra, Ujani, Baichoo, Shakuntala, Agalliu, Ilir, Kachambwa, Paidamoyo, Simonti, Corinne, Brown, Lyda, Tambe, Saanika, Kim, Michelle, Harlemon, Maxine, Jalloh, Mohamed, Muzondiwa, Dillon, Naidoo, Daphne, Ajayi, Olabode, Snyper, Nana, Niang, Lamine, Diop, Halimatou, Ndoye, Medina, Mensah, James, Darkwa-Abrahams, Afua, Biritwum, Richard, Adjei, Andrew, Adebiyi, Akindele, Shittu, Olayiwola, Ogunbiyi, Olufemi, Adebayo, Sikiru, Nwegbu, Maxwell, Ajibola, Hafees, Oluwole, Olabode, Jamda, Mustapha, Pentz, Audrey, Haiman, Christopher, Spies, Petrus, Van der Merwe, Andre, Cook, Michael, Chanock, Stephen J., Berndt, Sonja I., Watya, Stephen, Lubwama, Alex, Muchengeti, Mazvita, Doherty, Sean, Smyth, Natalie, Lounsbury, David, Fortier, Brian, Rohan, Thomas, Jacobson, Judith, Neugut, Alfred, Hsing, Ann, Gusev, Alexander, Aisuodionoe-Shadrach, Oseremen, Joffe, Maureen, Adusei, Ben, Gueye, Serigne, Fernandez, Pedro, McBride, Jo, Andrews, Caroline, Petersen, Lindsay, Lachance, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602179/
https://www.ncbi.nlm.nih.gov/pubmed/37886553
http://dx.doi.org/10.21203/rs.3.rs-3378303/v1

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