IL-17 Signaling in Primary Sclerosing Cholangitis Patient-Derived Organoids

The pathogenesis of primary sclerosing cholangitis (PSC) is unclear, although studies implicate IL-17A as an inflammatory mediator in this disease. However, a direct assessment of IL-17 signaling in PSC cholangiocytes is lacking. In this study we aimed to investigate the response of PSC extrahepatic...

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Detalles Bibliográficos
Autores principales: Garcia Moreno, Ana Sofia, Guicciardi, Maria Eugenia, Wixom, Alexander Q., Jessen, Erik, Yang, Jingchun, Ilyas, Sumera I., Bianchi, Jackie K., Pinto e Vairo, Filippo, Lazaridis, Konstantinos N., Gores, Gregory J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602181/
https://www.ncbi.nlm.nih.gov/pubmed/37886596
http://dx.doi.org/10.21203/rs.3.rs-3406046/v1

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