Anti‐PD‐1/Her2 Bispecific Antibody IBI315 Enhances the Treatment Effect of Her2‐Positive Gastric Cancer through Gasdermin B‐Cleavage Induced Pyroptosis (Adv. Sci. 30/2023)

Bispecific Antibodies In article number 2303908, Quan Zhou, Lisong Teng, and co‐workers developed a bispecific antibody (BsAb) that targets both PD1 in T cells and Her2 in tumor cells. This BsAb acts like a handcuff, firmly locking Her2(+) tumor cells in the hands of CD8(+) T cell policemen within t...

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Detalles Bibliográficos
Autores principales: Lin, Wu, Zhang, Yingzi, Yang, Yan, Lin, Ben, Zhu, Mengjia, Xu, Jinling, Chen, YiRan, Wu, Weiwei, Chen, Bingliang, Chen, Xiangliu, Liu, Jin, Wang, Haohao, Teng, Fei, Yu, Xiongfei, Wang, Haiyong, Lu, Jun, Zhou, Quan, Teng, Lisong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602503/
http://dx.doi.org/10.1002/advs.202370205

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