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Case report: Confusing lung signs – is the source of the disease in the lungs or intestines?

At the time of the spread of the COVID-19 epidemic, blurred lung signs suggested by imaging examination are particularly common. Novel coronavirus infection is mainly caused by respiratory symptoms. In the early stage of imaging examination, multiple small patchy shadows or ground glass shadows and...

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Detalles Bibliográficos
Autores principales: Zhao, Xiying, Mo, Jiahao, Zhang, Beiping, Zhang, Haiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602771/
https://www.ncbi.nlm.nih.gov/pubmed/37901397
http://dx.doi.org/10.3389/fmed.2023.1187208
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author Zhao, Xiying
Mo, Jiahao
Zhang, Beiping
Zhang, Haiyan
author_facet Zhao, Xiying
Mo, Jiahao
Zhang, Beiping
Zhang, Haiyan
author_sort Zhao, Xiying
collection PubMed
description At the time of the spread of the COVID-19 epidemic, blurred lung signs suggested by imaging examination are particularly common. Novel coronavirus infection is mainly caused by respiratory symptoms. In the early stage of imaging examination, multiple small patchy shadows or ground glass shadows and invasive shadows of both lungs are dominant. While the pulmonary involvement in Crohn’s disease (CD) is rare and not widely reported. For CD patients, the pulmonary manifestations do not belong to its routine symptoms. The lung involvement of CD patients is difficult to attract clinicians’ attention. If CD patients have vague lung manifestations but have no response to routine treatment, they should consider the respiratory diseases related to CD. We describe a rare case of granulomatous inflammation associated with Crohn’s disease. The patient do not respond to conventional treatment. The final treatment plan was CD immunomodulatory therapy (oral corticosteroids and azathioprine). After treatment, a review of the lung CT showed focal fibrosis and significant improvement in the lung lesions. It suggests that CD related respiratory diseases should be considered when CD patients have abnormal lung manifestations that do not respond to conventional treatment.
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spelling pubmed-106027712023-10-28 Case report: Confusing lung signs – is the source of the disease in the lungs or intestines? Zhao, Xiying Mo, Jiahao Zhang, Beiping Zhang, Haiyan Front Med (Lausanne) Medicine At the time of the spread of the COVID-19 epidemic, blurred lung signs suggested by imaging examination are particularly common. Novel coronavirus infection is mainly caused by respiratory symptoms. In the early stage of imaging examination, multiple small patchy shadows or ground glass shadows and invasive shadows of both lungs are dominant. While the pulmonary involvement in Crohn’s disease (CD) is rare and not widely reported. For CD patients, the pulmonary manifestations do not belong to its routine symptoms. The lung involvement of CD patients is difficult to attract clinicians’ attention. If CD patients have vague lung manifestations but have no response to routine treatment, they should consider the respiratory diseases related to CD. We describe a rare case of granulomatous inflammation associated with Crohn’s disease. The patient do not respond to conventional treatment. The final treatment plan was CD immunomodulatory therapy (oral corticosteroids and azathioprine). After treatment, a review of the lung CT showed focal fibrosis and significant improvement in the lung lesions. It suggests that CD related respiratory diseases should be considered when CD patients have abnormal lung manifestations that do not respond to conventional treatment. Frontiers Media S.A. 2023-10-12 /pmc/articles/PMC10602771/ /pubmed/37901397 http://dx.doi.org/10.3389/fmed.2023.1187208 Text en Copyright © 2023 Zhao, Mo, Zhang and Zhang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Zhao, Xiying
Mo, Jiahao
Zhang, Beiping
Zhang, Haiyan
Case report: Confusing lung signs – is the source of the disease in the lungs or intestines?
title Case report: Confusing lung signs – is the source of the disease in the lungs or intestines?
title_full Case report: Confusing lung signs – is the source of the disease in the lungs or intestines?
title_fullStr Case report: Confusing lung signs – is the source of the disease in the lungs or intestines?
title_full_unstemmed Case report: Confusing lung signs – is the source of the disease in the lungs or intestines?
title_short Case report: Confusing lung signs – is the source of the disease in the lungs or intestines?
title_sort case report: confusing lung signs – is the source of the disease in the lungs or intestines?
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602771/
https://www.ncbi.nlm.nih.gov/pubmed/37901397
http://dx.doi.org/10.3389/fmed.2023.1187208
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