Using combined single-cell gene expression, TCR sequencing and cell surface protein barcoding to characterize and track CD4+ T cell clones from murine tissues

Single-cell gene expression analysis using sequencing (scRNA-seq) has gained increased attention in the past decades for studying cellular transcriptional programs and their heterogeneity in an unbiased manner, and novel protocols allow the simultaneous measurement of gene expression, T-cell recepto...

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Detalles Bibliográficos
Autores principales: Nedwed, Annekathrin Silvia, Helbich, Sara Salome, Braband, Kathrin Luise, Volkmar, Michael, Delacher, Michael, Marini, Federico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602882/
https://www.ncbi.nlm.nih.gov/pubmed/37901204
http://dx.doi.org/10.3389/fimmu.2023.1241283

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