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BDNF-TrkB/proBDNF-p75(NTR) pathway regulation by lipid emulsion rescues bupivacaine-induced central neurotoxicity in rats

Bupivacaine (BPV) can cause severe central nervous system toxicity when absorbed into the blood circulation system. Rapid intravenous administration of lipid emulsion (LE) could be used to treat local anaesthetic toxicity. This study aimed to investigate the mechanism by which the BDNF-TrkB/proBDNF-...

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Detalles Bibliográficos
Autores principales:	Jia, Danting, Wang, Fang, Bai, Zhixia, Chen, Xuexin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603093/ https://www.ncbi.nlm.nih.gov/pubmed/37884604 http://dx.doi.org/10.1038/s41598-023-45572-8

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