Tandem-biocatalysis reactors constructed by topological evolution of CaCO(3) particles into hollow metal hydroxide spheres

Despite remarkable advances in the design and synthesis of hollow inorganic spheres (HISs), the harsh synthetic conditions have precluded the applications of HISs to biochemical and biological fields. Herein we report a biocompatible strategy for synthesizing metal hydroxide HISs (MH-HISs) by simply...

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Autores principales: Han, Sang Yeong, Kim, Nayoung, Yun, Gyeongwon, Lee, Hojae, Choi, Insung S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603116/
https://www.ncbi.nlm.nih.gov/pubmed/37884545
http://dx.doi.org/10.1038/s41467-023-42649-w
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author Han, Sang Yeong
Kim, Nayoung
Yun, Gyeongwon
Lee, Hojae
Choi, Insung S.
author_facet Han, Sang Yeong
Kim, Nayoung
Yun, Gyeongwon
Lee, Hojae
Choi, Insung S.
author_sort Han, Sang Yeong
collection PubMed
description Despite remarkable advances in the design and synthesis of hollow inorganic spheres (HISs), the harsh synthetic conditions have precluded the applications of HISs to biochemical and biological fields. Herein we report a biocompatible strategy for synthesizing metal hydroxide HISs (MH-HISs) by simply mixing CaCO(3) particles with metal ions in water. The ion-exchange reaction between Ca(2+) and metal ions leads to the structural and chemical evolution from solid CaCO(3) particles to hollow MH-HISs via core-shell and yolk-shell structures, while enabling the encapsulation of enzymes to the shells without loss of catalytic activities. The biocompatible protocol makes multienzymatic cascade reactions achievable, with great recyclability due to mechanical durability of MH-HISs.
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spelling pubmed-106031162023-10-28 Tandem-biocatalysis reactors constructed by topological evolution of CaCO(3) particles into hollow metal hydroxide spheres Han, Sang Yeong Kim, Nayoung Yun, Gyeongwon Lee, Hojae Choi, Insung S. Nat Commun Article Despite remarkable advances in the design and synthesis of hollow inorganic spheres (HISs), the harsh synthetic conditions have precluded the applications of HISs to biochemical and biological fields. Herein we report a biocompatible strategy for synthesizing metal hydroxide HISs (MH-HISs) by simply mixing CaCO(3) particles with metal ions in water. The ion-exchange reaction between Ca(2+) and metal ions leads to the structural and chemical evolution from solid CaCO(3) particles to hollow MH-HISs via core-shell and yolk-shell structures, while enabling the encapsulation of enzymes to the shells without loss of catalytic activities. The biocompatible protocol makes multienzymatic cascade reactions achievable, with great recyclability due to mechanical durability of MH-HISs. Nature Publishing Group UK 2023-10-26 /pmc/articles/PMC10603116/ /pubmed/37884545 http://dx.doi.org/10.1038/s41467-023-42649-w Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Han, Sang Yeong
Kim, Nayoung
Yun, Gyeongwon
Lee, Hojae
Choi, Insung S.
Tandem-biocatalysis reactors constructed by topological evolution of CaCO(3) particles into hollow metal hydroxide spheres
title Tandem-biocatalysis reactors constructed by topological evolution of CaCO(3) particles into hollow metal hydroxide spheres
title_full Tandem-biocatalysis reactors constructed by topological evolution of CaCO(3) particles into hollow metal hydroxide spheres
title_fullStr Tandem-biocatalysis reactors constructed by topological evolution of CaCO(3) particles into hollow metal hydroxide spheres
title_full_unstemmed Tandem-biocatalysis reactors constructed by topological evolution of CaCO(3) particles into hollow metal hydroxide spheres
title_short Tandem-biocatalysis reactors constructed by topological evolution of CaCO(3) particles into hollow metal hydroxide spheres
title_sort tandem-biocatalysis reactors constructed by topological evolution of caco(3) particles into hollow metal hydroxide spheres
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603116/
https://www.ncbi.nlm.nih.gov/pubmed/37884545
http://dx.doi.org/10.1038/s41467-023-42649-w
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