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FHL1 promotes chikungunya and o’nyong-nyong virus infection and pathogenesis with implications for alphavirus vaccine design
Arthritogenic alphaviruses are positive-strand RNA viruses that cause debilitating musculoskeletal diseases affecting millions worldwide. A recent discovery identified the four-and-a-half-LIM domain protein 1 splice variant A (FHL1A) as a crucial host factor interacting with the hypervariable domain...
Autores principales: | Ng, Wern Hann, Liu, Xiang, Ling, Zheng L., Santos, Camilla N. O., Magalhães, Lucas S., Kueh, Andrew J., Herold, Marco J., Taylor, Adam, Freitas, Joseph R., Koit, Sandra, Wang, Sainan, Lloyd, Andrew R., Teixeira, Mauro M., Merits, Andres, Almeida, Roque P., King, Nicholas J. C., Mahalingam, Suresh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603155/ https://www.ncbi.nlm.nih.gov/pubmed/37884534 http://dx.doi.org/10.1038/s41467-023-42330-2 |
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