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Deleterious and protective effects of epothilone-D alone and in the context of amyloid β- and tau-induced alterations

Amyloid-β (Aβ) and hyperphosphorylated tau (P-tau) are Alzheimer’s disease (AD) biomarkers that interact in a complex manner to induce most of the cognitive and brain alterations observed in this disease. Since the neuronal cytoskeleton is a common downstream pathological target of tau and Aβ, which...

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Detalles Bibliográficos
Autores principales: Robles-Gómez, Ángel Abdiel, Ordaz, Benito, Lorea-Hernández, Jonathan-Julio, Peña-Ortega, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603193/
https://www.ncbi.nlm.nih.gov/pubmed/37900942
http://dx.doi.org/10.3389/fnmol.2023.1198299