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Characteristics and evaluation of atherosclerotic plaques: an overview of state-of-the-art techniques
Atherosclerosis is an important cause of cerebrovascular and cardiovascular disease (CVD). Lipid infiltration, inflammation, and altered vascular stress are the critical mechanisms that cause atherosclerotic plaque formation. The hallmarks of the progression of atherosclerosis include plaque ulcerat...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603250/ https://www.ncbi.nlm.nih.gov/pubmed/37900593 http://dx.doi.org/10.3389/fneur.2023.1159288 |
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author | He, Zhiwei Luo, Jiaying Lv, Mengna Li, Qingwen Ke, Wei Niu, Xuan Zhang, Zhaohui |
author_facet | He, Zhiwei Luo, Jiaying Lv, Mengna Li, Qingwen Ke, Wei Niu, Xuan Zhang, Zhaohui |
author_sort | He, Zhiwei |
collection | PubMed |
description | Atherosclerosis is an important cause of cerebrovascular and cardiovascular disease (CVD). Lipid infiltration, inflammation, and altered vascular stress are the critical mechanisms that cause atherosclerotic plaque formation. The hallmarks of the progression of atherosclerosis include plaque ulceration, rupture, neovascularization, and intraplaque hemorrhage, all of which are closely associated with the occurrence of CVD. Assessing the severity of atherosclerosis and plaque vulnerability is crucial for the prevention and treatment of CVD. Integrating imaging techniques for evaluating the characteristics of atherosclerotic plaques with computer simulations yields insights into plaque inflammation levels, spatial morphology, and intravascular stress distribution, resulting in a more realistic and accurate estimation of plaque state. Here, we review the characteristics and advancing techniques used to analyze intracranial and extracranial atherosclerotic plaques to provide a comprehensive understanding of atheroma. |
format | Online Article Text |
id | pubmed-10603250 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-106032502023-10-28 Characteristics and evaluation of atherosclerotic plaques: an overview of state-of-the-art techniques He, Zhiwei Luo, Jiaying Lv, Mengna Li, Qingwen Ke, Wei Niu, Xuan Zhang, Zhaohui Front Neurol Neurology Atherosclerosis is an important cause of cerebrovascular and cardiovascular disease (CVD). Lipid infiltration, inflammation, and altered vascular stress are the critical mechanisms that cause atherosclerotic plaque formation. The hallmarks of the progression of atherosclerosis include plaque ulceration, rupture, neovascularization, and intraplaque hemorrhage, all of which are closely associated with the occurrence of CVD. Assessing the severity of atherosclerosis and plaque vulnerability is crucial for the prevention and treatment of CVD. Integrating imaging techniques for evaluating the characteristics of atherosclerotic plaques with computer simulations yields insights into plaque inflammation levels, spatial morphology, and intravascular stress distribution, resulting in a more realistic and accurate estimation of plaque state. Here, we review the characteristics and advancing techniques used to analyze intracranial and extracranial atherosclerotic plaques to provide a comprehensive understanding of atheroma. Frontiers Media S.A. 2023-10-12 /pmc/articles/PMC10603250/ /pubmed/37900593 http://dx.doi.org/10.3389/fneur.2023.1159288 Text en Copyright © 2023 He, Luo, Lv, Li, Ke, Niu and Zhang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Neurology He, Zhiwei Luo, Jiaying Lv, Mengna Li, Qingwen Ke, Wei Niu, Xuan Zhang, Zhaohui Characteristics and evaluation of atherosclerotic plaques: an overview of state-of-the-art techniques |
title | Characteristics and evaluation of atherosclerotic plaques: an overview of state-of-the-art techniques |
title_full | Characteristics and evaluation of atherosclerotic plaques: an overview of state-of-the-art techniques |
title_fullStr | Characteristics and evaluation of atherosclerotic plaques: an overview of state-of-the-art techniques |
title_full_unstemmed | Characteristics and evaluation of atherosclerotic plaques: an overview of state-of-the-art techniques |
title_short | Characteristics and evaluation of atherosclerotic plaques: an overview of state-of-the-art techniques |
title_sort | characteristics and evaluation of atherosclerotic plaques: an overview of state-of-the-art techniques |
topic | Neurology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603250/ https://www.ncbi.nlm.nih.gov/pubmed/37900593 http://dx.doi.org/10.3389/fneur.2023.1159288 |
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