Niclosamide as a chemical probe for analyzing SARS-CoV-2 modulation of host cell lipid metabolism

INTRODUCTION: SARS-CoV-2 subverts host cell processes to facilitate rapid replication and dissemination, and this leads to pathological inflammation. METHODS: We used niclosamide (NIC), a poorly soluble anti-helminth drug identified initially for repurposed treatment of COVID-19, which activates the...

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Detalles Bibliográficos
Autores principales: Garrett, Timothy J., Coatsworth, Heather, Mahmud, Iqbal, Hamerly, Timothy, Stephenson, Caroline J., Ayers, Jasmine B., Yazd, Hoda S., Miller, Megan R., Lednicky, John A., Dinglasan, Rhoel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603251/
https://www.ncbi.nlm.nih.gov/pubmed/37901834
http://dx.doi.org/10.3389/fmicb.2023.1251065

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