Investigation of the human metabolism and disposition of the prolyl hydrolase inhibitor daprodustat using IV microtracer with Entero‐Test bile string

Daprodustat is an oral small molecule hypoxia‐inducible factor (HIF) prolyl hydroxylase inhibitor (PHI) approved in Japan and the United States for the treatment of anemia associated with chronic kidney disease. This phase 1, nonrandomized, 2‐period, crossover study in 6 healthy men characterized an...

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Detalles Bibliográficos
Autores principales: Tai, Guoying, Xia, Fangming, Chen, Cathy, Pereira, Adrian, Pirhalla, Jill, Miao, Xiusheng, Young, Graeme, Beaumont, Claire, Chen, Liangfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603292/
https://www.ncbi.nlm.nih.gov/pubmed/37885335
http://dx.doi.org/10.1002/prp2.1145

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