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A Rare Pediatric Encounter: Transverse Myelitis With Subacute Bilateral Lower Extremity Weakness

This case report provides a comprehensive overview of a rare instance of transverse myelitis (TM) in an 11-year-old male who presented with subacute bilateral lower extremity weakness, sensory loss, and bowel/bladder dysfunction. Diagnostic evaluations, including MRI and cerebrospinal fluid (CSF) an...

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Autores principales: Arif, Aleena, Masood, Quratulain Fatima, Chowdhury, Nadia M, Affaf, Maryam, Thabrew Wijeratne, Gavitha N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603305/
https://www.ncbi.nlm.nih.gov/pubmed/37900361
http://dx.doi.org/10.7759/cureus.46041
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author Arif, Aleena
Masood, Quratulain Fatima
Chowdhury, Nadia M
Affaf, Maryam
Thabrew Wijeratne, Gavitha N
author_facet Arif, Aleena
Masood, Quratulain Fatima
Chowdhury, Nadia M
Affaf, Maryam
Thabrew Wijeratne, Gavitha N
author_sort Arif, Aleena
collection PubMed
description This case report provides a comprehensive overview of a rare instance of transverse myelitis (TM) in an 11-year-old male who presented with subacute bilateral lower extremity weakness, sensory loss, and bowel/bladder dysfunction. Diagnostic evaluations, including MRI and cerebrospinal fluid (CSF) analysis, confirmed TM. Management with high-dose intravenous corticosteroids and rehabilitative therapies led to symptom stabilization and modest recovery, although some permanent deficits are anticipated. The report highlights the importance of prompt diagnosis and intervention in pediatric patients with acute neurologic symptoms localized to the spinal cord. It contributes to the existing literature by detailing the clinical and diagnostic features of pediatric TM, aiding in early recognition and management to minimize permanent disability. Future research should focus on understanding the underlying pathophysiology with a view to developing targeted therapies.
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spelling pubmed-106033052023-10-28 A Rare Pediatric Encounter: Transverse Myelitis With Subacute Bilateral Lower Extremity Weakness Arif, Aleena Masood, Quratulain Fatima Chowdhury, Nadia M Affaf, Maryam Thabrew Wijeratne, Gavitha N Cureus Pediatrics This case report provides a comprehensive overview of a rare instance of transverse myelitis (TM) in an 11-year-old male who presented with subacute bilateral lower extremity weakness, sensory loss, and bowel/bladder dysfunction. Diagnostic evaluations, including MRI and cerebrospinal fluid (CSF) analysis, confirmed TM. Management with high-dose intravenous corticosteroids and rehabilitative therapies led to symptom stabilization and modest recovery, although some permanent deficits are anticipated. The report highlights the importance of prompt diagnosis and intervention in pediatric patients with acute neurologic symptoms localized to the spinal cord. It contributes to the existing literature by detailing the clinical and diagnostic features of pediatric TM, aiding in early recognition and management to minimize permanent disability. Future research should focus on understanding the underlying pathophysiology with a view to developing targeted therapies. Cureus 2023-09-26 /pmc/articles/PMC10603305/ /pubmed/37900361 http://dx.doi.org/10.7759/cureus.46041 Text en Copyright © 2023, Arif et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pediatrics
Arif, Aleena
Masood, Quratulain Fatima
Chowdhury, Nadia M
Affaf, Maryam
Thabrew Wijeratne, Gavitha N
A Rare Pediatric Encounter: Transverse Myelitis With Subacute Bilateral Lower Extremity Weakness
title A Rare Pediatric Encounter: Transverse Myelitis With Subacute Bilateral Lower Extremity Weakness
title_full A Rare Pediatric Encounter: Transverse Myelitis With Subacute Bilateral Lower Extremity Weakness
title_fullStr A Rare Pediatric Encounter: Transverse Myelitis With Subacute Bilateral Lower Extremity Weakness
title_full_unstemmed A Rare Pediatric Encounter: Transverse Myelitis With Subacute Bilateral Lower Extremity Weakness
title_short A Rare Pediatric Encounter: Transverse Myelitis With Subacute Bilateral Lower Extremity Weakness
title_sort rare pediatric encounter: transverse myelitis with subacute bilateral lower extremity weakness
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603305/
https://www.ncbi.nlm.nih.gov/pubmed/37900361
http://dx.doi.org/10.7759/cureus.46041
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