Cargando…

Sustained Survival Benefit in Recurrent Medulloblastoma by a Metronomic Antiangiogenic Regimen: A Nonrandomized Controlled Trial

IMPORTANCE: Medulloblastoma recurrence in patients who have previously received irradiation has a dismal prognosis and lacks a standard salvage regimen. OBJECTIVE: To evaluate the response rate of pediatric patients with medulloblastoma recurrence using an antiangiogenic metronomic combinatorial app...

Descripción completa

Detalles Bibliográficos
Autores principales:	Peyrl, Andreas, Chocholous, Monika, Sabel, Magnus, Lassaletta, Alvaro, Sterba, Jaroslav, Leblond, Pierre, Nysom, Karsten, Torsvik, Ingrid, Chi, Susan N., Perwein, Thomas, Jones, Neil, Holm, Stefan, Nyman, Per, Mörse, Helena, Öberg, Anders, Weiler-Wichtl, Liesa, Leiss, Ulrike, Haberler, Christine, Schmook, Maresa T., Mayr, Lisa, Dieckmann, Karin, Kool, Marcel, Gojo, Johannes, Azizi, Amedeo A., André, Nicolas, Kieran, Mark, Slavc, Irene
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Medical Association 2023
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603581/ https://www.ncbi.nlm.nih.gov/pubmed/37883081 http://dx.doi.org/10.1001/jamaoncol.2023.4437

Ejemplares similares

Improved Long-Term Survival of Patients with Recurrent Medulloblastoma Treated with a “MEMMAT-like” Metronomic Antiangiogenic Approach
por: Slavc, Irene, et al.
Publicado: (2022)

RARE-20. A RARE CASE OF A PRIMARY CENTRAL NERVOUS SYSTEM NEUROENDOCRINE CARCINOMA AND SUCCESSFULL THERAPY IN A FIVE-YEAR-OLD CHILD
por: Stepien, Natalia, et al.
Publicado: (2021)

Atypical teratoid rhabdoid tumor: improved long-term survival with an intensive multimodal therapy and delayed radiotherapy. The Medical University of Vienna Experience 1992–2012
por: Slavc, Irene, et al.
Publicado: (2014)

ETMR-10. EARLY FOCAL RADIOTHERAPY AND TEMOZOLOMIDE FOLLOWING COMPLETE RESECTION APPEAR SUPERIOR TO INTENSIVE CHEMOTHERAPY AND DELAYED RADIOTHERAPY IN CHILDREN WITH EMBRYONAL TUMORS WITH MULTILAYERED ROSETTES (ETMR)
por: Mayr, Lisa, et al.
Publicado: (2020)

Bridging the gap: A quality improvement project to implement psychosocial care standards into clinical practice in pediatric oncology
por: Weiler-Wichtl, Liesa J., et al.
Publicado: (2023)

SWK-05. Clinical social work in pediatric neuro-oncology – A research project on the social dimension using social diagnostics
por: Krottendorfer, Kerstin, et al.
Publicado: (2022)

Unique Finding of a Primary Central Nervous System Neuroendocrine Carcinoma in a 5-Year-Old Child: A Case Report
por: Stepien, Natalia, et al.
Publicado: (2022)

MBCL-43. RECURRENT MEDULLOBLASTOMA – LONG-TERM SURVIVAL WITH A “MEMMAT” BASED ANTIANGIOGENIC APPROACH
por: Slavc, Irene, et al.
Publicado: (2020)

Potential Importance of Early Focal Radiotherapy Following Gross Total Resection for Long-Term Survival in Children With Embryonal Tumors With Multilayered Rosettes
por: Mayr, Lisa, et al.
Publicado: (2020)

Chromosome 1q gain and tenascin-C expression are candidate markers to define different risk groups in pediatric posterior fossa ependymoma
por: Araki, Asuka, et al.
Publicado: (2016)

Good to know – This is PPIE! Development of a training tool for public and patient involvement and engagement in pediatric oncological research
por: Weiler‐Wichtl, Liesa Josephine, et al.
Publicado: (2023)

Does the interval from tumour surgery to radiotherapy influence survival in paediatric high grade glioma?
por: Azizi, Amedeo A., et al.
Publicado: (2018)

QOL-30. Positive Effects of a psychological preparation program for MRI in children with cognitive issues – how to best meet the patients’ needs
por: Weiler-Wichtl, Liesa Josephine, et al.
Publicado: (2022)

Personalized Treatment of H3K27M-Mutant Pediatric Diffuse Gliomas Provides Improved Therapeutic Opportunities
por: Gojo, Johannes, et al.
Publicado: (2020)

DDEL-03. LONG-TERM INTRAVENTRICULAR THERAPY ALTERNATING ETOPOSIDE AND LIPOSOMAL CYTARABINE: EXPERIENCE IN 75 CHILDREN AND ADOLESCENTS WITH MALIGNANT BRAIN TUMORS
por: Stepien, Natalia, et al.
Publicado: (2020)

Infiltrative gliomas of the thalamus in children: the role of surgery in the era of H3 K27M mutant midline gliomas
por: Dorfer, Christian, et al.
Publicado: (2020)

Prospective Evaluation of Kidney Function in Long-Term Survivors of Pediatric CNS Tumors
por: Stepien, Natalia, et al.
Publicado: (2022)

Initial Evidence for Positive Effects of a Psychological Preparation Program for MRI “iMReady” in Children with Neurofibromatosis Type I and Brain Tumors—How to Meet the Patients’ Needs Best
por: Weiler-Wichtl, Liesa Josephine, et al.
Publicado: (2023)

High impact of miRNA-4521 on FOXM1 expression in medulloblastoma
por: Senfter, Daniel, et al.
Publicado: (2019)

Pharmacokinetics of Bevacizumab in Three Patients Under the Age of 3 Years with CNS Malignancies
por: Gojo, Johannes, et al.
Publicado: (2017)

QOL-35. School reentry of children and adolescents with a brain tumor: can we improve family-school-hospital cooperation? An analysis of supportive and inhibiting factors as a result of a pilot project
por: Leiss, Ulrike, et al.
Publicado: (2022)

The Site of Origin of Medulloblastoma: Surgical Observations Correlated to Molecular Groups
por: Ciobanu-Caraus, Olga, et al.
Publicado: (2023)

SURG-02. The site of origin of medulloblastoma: Does the neurosurgical perspective support the current concept from molecular data?
por: Ciobanu-Caraus, Olga, et al.
Publicado: (2022)

Pharmacokinetics of metronomic temozolomide in cerebrospinal fluid of children with malignant central nervous system tumors
por: Büsker, Sören, et al.
Publicado: (2022)

Cerebellar pilocytic astrocytoma in childhood: Investigating the long-term impact of surgery on cognitive performance and functional outcome
por: Pletschko, Thomas, et al.
Publicado: (2017)

HGG-44. DEFECTS OF MISMATCH REPAIR PROTEINS IN PEDIATRIC HIGH GRADE GLIOMAS
por: Haberler, Christine, et al.
Publicado: (2020)

Novel Insights into Diagnosis, Biology, and Treatment of Primary Diffuse Leptomeningeal Melanomatosis
por: Baumgartner, Alicia, et al.
Publicado: (2021)

Evaluating the diagnostic validity of the cerebellar cognitive affective syndrome (CCAS) in pediatric posterior fossa tumor patients
por: Hoffmann-Lamplmair, Doris, et al.
Publicado: (2022)

Cerebrospinal Fluid Penetration and Combination Therapy of Entrectinib for Disseminated ROS1/NTRK-Fusion Positive Pediatric High-Grade Glioma
por: Mayr, Lisa, et al.
Publicado: (2020)

Placement of EVD in pediatric posterior fossa tumors: safe and efficient or old-fashioned? The Vienna experience
por: Hedrich, Cora, et al.
Publicado: (2023)

QOL-31. A psychosocial support program for young adult childhood cancer survivors in Austria: a qualitative evaluation study
por: Pletschko, Thomas, et al.
Publicado: (2022)

A Psychosocial Support Program for Young Adult Childhood Cancer Survivors in Austria: a Qualitative Evaluation Study
por: Pletschko, Thomas, et al.
Publicado: (2021)

Cerebrospinal fluid penetration of targeted therapeutics in pediatric brain tumor patients
por: Guntner, Armin Sebastian, et al.
Publicado: (2020)

Sociocultural variables have a major impact on participation in patients treated for paediatric posterior fossa tumours
por: Hoffmann‐Lamplmair, Doris, et al.
Publicado: (2022)

DDEL-05. Intraventricular therapy with topotecan is feasible and safe: Experience in 50 pediatric patients with various malignant brain tumors
por: Peyrl, Andreas, et al.
Publicado: (2022)

Proof-of-Concept for Liquid Biopsy Disease Monitoring of MYC-Amplified Group 3 Medulloblastoma by Droplet Digital PCR
por: Stepien, Natalia, et al.
Publicado: (2023)

Clinical applicability of miR517a detection in liquid biopsies of ETMR patients
por: Madlener, Sibylle, et al.
Publicado: (2023)

ATRT-07. CLINICAL APPLICABILITY OF C19MC MIRNA DETECTION IN LIQUID BIOPSIES OF ETMR PATIENTS
por: Madlener, Sibylle, et al.
Publicado: (2023)

HGG-19. CLINICAL RESPONSE TO THE PDGFRA/KIT INHIBITOR AVAPRITINIB IN PEDIATRIC AND YOUNG ADULT HIGH-GRADE GLIOMA PATIENTS WITH H3K27M OR PDGFRA GENOMIC ALTERATIONS
por: Trissal, Maria, et al.
Publicado: (2023)

Management of choroid plexus tumors—an institutional experience
por: Hosmann, Arthur, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_oacehbgoj125fk2h6ivt4b9trd