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Design of an Anti-HMGB1 Synthetic Antibody for In Vivo Ischemic/Reperfusion Injury Therapy

[Image: see text] High-mobility group box 1 (HMGB1) is a multifunctional protein. Upon injury or infection, HMGB1 is passively released from necrotic and activated dendritic cells and macrophages, where it functions as a cytokine, acting as a ligand for RAGE, a major receptor of innate immunity stim...

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Detalles Bibliográficos
Autores principales:	Koide, Hiroyuki, Kiyokawa, Chiaki, Okishima, Anna, Saito, Kaito, Yoshimatsu, Keiichi, Fukuta, Tatsuya, Hoshino, Yu, Asai, Tomohiro, Nishimura, Yuri, Miura, Yoshiko, Oku, Naoto, Shea, Kenneth J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603801/ https://www.ncbi.nlm.nih.gov/pubmed/37844138 http://dx.doi.org/10.1021/jacs.3c06799

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