The Activation of JAK/STAT3 Signaling and the Complement System Modulate Inflammation in the Primary Human Dermal Fibroblasts of PXE Patients

Previous studies revealed a link between inflammation and overactivation of the Janus kinase (JAK)/signal transducer and activator of transcription (STAT) signaling in syndromes associated with aging. Pseudoxanthoma elasticum (PXE), a rare autosomal-recessive disorder, arises from mutations in ATP-b...

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Detalles Bibliográficos
Autores principales: Lindenkamp, Christopher, Plümers, Ricarda, Osterhage, Michel R., Vanakker, Olivier M., Van Wynsberghe, Judith, Knabbe, Cornelius, Hendig, Doris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603841/
https://www.ncbi.nlm.nih.gov/pubmed/37893046
http://dx.doi.org/10.3390/biomedicines11102673

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