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Antimicrobial and Adjuvant Potencies of Di-n-alkyl Substituted Diazalariat Ethers

Lariat ethers are macrocyclic polyethers—crown ethers—to which sidearms are appended. 4,13-Diaza-18-crown-6 having twin alkyl chains at the nitrogens show biological activity. They exhibit antibiotic activity, but when co-administered at with an FDA-approved antibiotic, the latter’s potency is often...

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Detalles Bibliográficos
Autores principales: Patel, Mohit B., Spikes, Helena, Bailey, Robert S., Connell, Thomas, Gill, Hannah, Gokel, Michael R., Harris, Rebecca, Meisel, Joseph W., Negin, Saeedeh, Yin, Shanheng Andrew, Gokel, George W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603992/
https://www.ncbi.nlm.nih.gov/pubmed/37887214
http://dx.doi.org/10.3390/antibiotics12101513