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Zero-Mode Waveguide Nanowells for Single-Molecule Detection in Living Cells

[Image: see text] Single-molecule fluorescence imaging experiments generally require sub-nanomolar protein concentrations to isolate single protein molecules, which makes such experiments challenging in live cells due to high intracellular protein concentrations. Here, we show that single-molecule o...

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Detalles Bibliográficos
Autores principales: Yang, Sora, Klughammer, Nils, Barth, Anders, Tanenbaum, Marvin E., Dekker, Cees
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604100/
https://www.ncbi.nlm.nih.gov/pubmed/37791900
http://dx.doi.org/10.1021/acsnano.3c05959