Klotho Null Mutation Indirectly Leads to Age-Related Lacrimal Gland Degeneration in Mutant Mice

SIMPLE SUMMARY: The Klotho gene null mutation has been shown to cause accelerated senescence in many organs. Nevertheless, whether the mutation may cause lacrimal gland dysfunction and degeneration has not been elucidated. This study shows that the Klotho null mutation leads to reduced tear volume w...

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Detalles Bibliográficos
Autores principales: Wu, Chun-Yen, Song, Da-Fong, Lu, Tsung-Han, Chen, Zhi-Jia, Tsai, Su-Min, Liu, Ya-Jing, Chang, Han-Hsin, Lin, David Pei-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604155/
https://www.ncbi.nlm.nih.gov/pubmed/37887038
http://dx.doi.org/10.3390/biology12101328

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