Cargando…

The NADPH Link between the Renin Angiotensin System and the Antioxidant Mechanisms in Dopaminergic Neurons

The renin angiotensin system (RAS) has several components including signaling peptides, enzymes, and membrane receptors. The effort in characterizing this system in the periphery has led to the approval of a class of antihypertensives. Much less is known about RAS in the central nervous system. The...

Descripción completa

Detalles Bibliográficos
Autores principales:	Franco, Rafael, Serrano-Marín, Joan, Navarro, Gemma, Rivas-Santisteban, Rafael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604245/ https://www.ncbi.nlm.nih.gov/pubmed/37891948 http://dx.doi.org/10.3390/antiox12101869

Ejemplares similares

Functional Complexes of Angiotensin-Converting Enzyme 2 and Renin-Angiotensin System Receptors: Expression in Adult but Not Fetal Lung Tissue
por: Franco, Rafael, et al.
Publicado: (2020)

Novel Interactions Involving the Mas Receptor Show Potential of the Renin–Angiotensin system in the Regulation of Microglia Activation: Altered Expression in Parkinsonism and Dyskinesia
por: Rivas-Santisteban, Rafael, et al.
Publicado: (2021)

Genes Implicated in Familial Parkinson’s Disease Provide a Dual Picture of Nigral Dopaminergic Neurodegeneration with Mitochondria Taking Center Stage
por: Franco, Rafael, et al.
Publicado: (2021)

An ACE2/Mas-related receptor MrgE axis in dopaminergic neuron mitochondria
por: Valenzuela, Rita, et al.
Publicado: (2021)

Renin angiotensin system and gender differences in dopaminergic degeneration
por: Rodriguez-Perez, Ana I, et al.
Publicado: (2011)

Brain renin-angiotensin system and dopaminergic cell vulnerability
por: Labandeira-García, Jose L., et al.
Publicado: (2014)

The intracellular renin-angiotensin system: Friend or foe. Some light from the dopaminergic neurons
por: Labandeira-Garcia, Jose L., et al.
Publicado: (2021)

N-Methyl-D-aspartate (NMDA) and cannabinoid CB(2) receptors form functional complexes in cells of the central nervous system: insights into the therapeutic potential of neuronal and microglial NMDA receptors
por: Rivas-Santisteban, Rafael, et al.
Publicado: (2021)

The Expression of Cellular Prion Protein, PrPC, Favors pTau Propagation and Blocks NMDAR Signaling in Primary Cortical Neurons
por: Rivas-Santisteban, Rafael, et al.
Publicado: (2023)

NADPH Oxidase and the Degeneration of Dopaminergic Neurons in Parkinsonian Mice
por: Hernandes, Marina S., et al.
Publicado: (2013)

Angiotensin AT(1) and AT(2) receptor heteromer expression in the hemilesioned rat model of Parkinson’s disease that increases with levodopa-induced dyskinesia
por: Rivas-Santisteban, Rafael, et al.
Publicado: (2020)

NADPH-Oxidase, Rho-Kinase and Autophagy Mediate the (Pro)renin-Induced Pro-Inflammatory Microglial Response and Enhancement of Dopaminergic Neuron Death
por: Lopez-Lopez, Andrea, et al.
Publicado: (2021)

Adenosine Receptor Antagonists to Combat Cancer and to Boost Anti-Cancer Chemotherapy and Immunotherapy
por: Franco, Rafael, et al.
Publicado: (2021)

The Old and New Visions of Biased Agonism Through the Prism of Adenosine Receptor Signaling and Receptor/Receptor and Receptor/Protein Interactions
por: Franco, Rafael, et al.
Publicado: (2021)

Involvement of dopaminergic signaling in the cross talk between the renin-angiotensin system and inflammation
por: Campos, Javier, et al.
Publicado: (2020)

The Renin–Angiotensin System Modulates Dopaminergic Neurotransmission: A New Player on the Scene
por: Kobiec, Tamara, et al.
Publicado: (2021)

Role of NADPH oxidase in the vascular reactivity and superoxide generation in the intrauterine undernourished rats: involvement of the renin–angiotensin system
por: Franco, MCP, et al.
Publicado: (2003)

Microglial Adenosine Receptors: From Preconditioning to Modulating the M1/M2 Balance in Activated Cells
por: Franco, Rafael, et al.
Publicado: (2021)

Identification of the Ghrelin and Cannabinoid CB(2) Receptor Heteromer Functionality and Marked Upregulation in Striatal Neurons from Offspring of Mice under a High-Fat Diet
por: Lillo, Jaume, et al.
Publicado: (2021)

Interactions between ibuprofen, ACE2, renin‐angiotensin system, and spike protein in the lung. Implications for COVID‐19
por: Valenzuela, Rita, et al.
Publicado: (2021)

Microbiota and Other Preventive Strategies and Non-genetic Risk Factors in Parkinson’s Disease
por: Franco, Rafael, et al.
Publicado: (2020)

Clozapine metabolites protect dopaminergic neurons through inhibition of microglial NADPH oxidase
por: Jiang, Lulu, et al.
Publicado: (2016)

Adenosine A(2A) Receptor Antagonists Affects NMDA Glutamate Receptor Function. Potential to Address Neurodegeneration in Alzheimer’s Disease
por: Franco, Rafael, et al.
Publicado: (2020)

5-Hydroxytryptamine, Glutamate, and ATP: Much More Than Neurotransmitters
por: Franco, Rafael, et al.
Publicado: (2021)

Mitochondrial-dependent mechanisms are involved in angiotensin II-induced apoptosis in dopaminergic neurons
por: Ou, Zhou, et al.
Publicado: (2016)

Mitochondrial angiotensin receptors in dopaminergic neurons. Role in cell protection and aging-related vulnerability to neurodegeneration
por: Valenzuela, Rita, et al.
Publicado: (2016)

Vaccines against components of the renin–angiotensin system
por: Garay-Gutiérrez, Noé Francisco, et al.
Publicado: (2020)

Antioxidant Defense Mechanisms in Erythrocytes and in the Central Nervous System
por: Franco, Rafael, et al.
Publicado: (2019)

Hormetic and Mitochondria-Related Mechanisms of Antioxidant Action of Phytochemicals
por: Franco, Rafael, et al.
Publicado: (2019)

COVID-19 and the Renin-Angiotensin System
por: Malha, Line, et al.
Publicado: (2020)

What’s new in the renin-angiotensin system?: What’s new in the renin-angiotensin system?
por: Smith, A. I., et al.
Publicado: (2004)

Antagonization of OX(1) Receptor Potentiates CB(2) Receptor Function in Microglia from APP(Sw/Ind) Mice Model
por: Raïch, Iu, et al.
Publicado: (2022)

Emergence and evolution of the renin–angiotensin–aldosterone system
por: Fournier, David, et al.
Publicado: (2012)

Three key proteases – angiotensin-I-converting enzyme (ACE), ACE2 and renin – within and beyond the renin-angiotensin system
por: Guang, Cuie, et al.
Publicado: (2012)

Dopaminergic neurons: linking longevity with reproduction?
por: Tian, Xiaolin
Publicado: (2022)

Major pathways of the reno–cardiovascular link: the sympathetic and renin–angiotensin systems
por: Blankestijn, Peter J, et al.
Publicado: (2011)

The systemic and hepatic alternative renin–angiotensin system is activated in liver cirrhosis, linked to endothelial dysfunction and inflammation
por: Hartl, Lukas, et al.
Publicado: (2023)

Renin–angiotensin system: Basic and clinical aspects—A general perspective
por: Vargas Vargas, Rafael Antonio, et al.
Publicado: (2022)

Renin–angiotensin system: Basic and clinical aspects—A general perspective
por: Vargas Vargas, Rafael Antonio, et al.
Publicado: (2022)

The Renin-Angiotensin System Textbook
por: Cumming, Allan D
Publicado: (1994)

Cannot write session to /tmp/vufind_sessions/sess_ilu6gj7k85mud4tk63jak1qt6o