Quality by Design (QbD) and Design of Experiments (DOE) as a Strategy for Tuning Lipid Nanoparticle Formulations for RNA Delivery

The successful development of nonviral delivery systems for nucleic acids has been reported extensively over the past years. Increasingly employed to improve the delivery efficiency and therapeutic efficacy of RNA are lipid nanoparticles (LNPs). Many of the various critical formulation parameters ca...

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Detalles Bibliográficos
Autores principales: Gurba-Bryśkiewicz, Lidia, Maruszak, Wioleta, Smuga, Damian A., Dubiel, Krzysztof, Wieczorek, Maciej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604315/
https://www.ncbi.nlm.nih.gov/pubmed/37893125
http://dx.doi.org/10.3390/biomedicines11102752

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604315/
https://www.ncbi.nlm.nih.gov/pubmed/37893125
http://dx.doi.org/10.3390/biomedicines11102752

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