Cargando…

Aminopeptidase N/CD13 Crosslinking Promotes the Activation and Membrane Expression of Integrin CD11b/CD18 †

The β2 integrin CD11b/CD18, also known as complement receptor 3 (CR3), and the moonlighting protein aminopeptidase N (CD13), are two myeloid immune receptors with overlapping activities: adhesion, migration, phagocytosis of opsonized particles, and respiratory burst induction. Given their common fun...

Descripción completa

Detalles Bibliográficos
Autores principales:	Díaz-Alvarez, Laura, Martínez-Sánchez, Mariana Esther, Gray, Eleanor, Pérez-Figueroa, Erandi, Ortega, Enrique
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604325/ https://www.ncbi.nlm.nih.gov/pubmed/37892170 http://dx.doi.org/10.3390/biom13101488

Ejemplares similares

Crosslinking of membrane CD13 in human neutrophils mediates phagocytosis and production of reactive oxygen species, neutrophil extracellular traps and proinflammatory cytokines
por: Pérez-Figueroa, Erandi, et al.
Publicado: (2022)

Aminopeptidase N (CD13) Is Involved in Phagocytic Processes in Human Dendritic Cells and Macrophages
por: Villaseñor-Cardoso, Mónica I., et al.
Publicado: (2013)

CD13/aminopeptidase N in collagen vascular diseases
por: Dan, Hirohumi, et al.
Publicado: (2003)

CD13/aminopeptidase N and murine cytomegalovirus infection
por: Kasman, Laura M.
Publicado: (2005)

A peptide derived from the intercellular adhesion molecule-2 regulates the avidity of the leukocyte integrins CD11b/CD18 and CD11c/CD18
Publicado: (1995)

Induction of Atrial Fibrillation by Neutrophils Critically Depends on CD11b/CD18 Integrins
por: Friedrichs, Kai, et al.
Publicado: (2014)

Regulated expression and function of CD11c/CD18 integrin on human B lymphocytes. Relation between attachment to fibrinogen and triggering of proliferation through CD11c/CD18
Publicado: (1991)

Molecular mechanism of leukocidin GH–integrin CD11b/CD18 recognition and species specificity
por: Trstenjak, Nikolina, et al.
Publicado: (2020)

Expressions of CD11a, CD11b, and CD11c integrin proteins in rats with myocardial hypertrophy
por: Mu, Lingmin, et al.
Publicado: (2014)

Immunoelectron microscopic single and double labelling of aminopeptidase N (CD 13) and dipeptidyl peptidase IV (CD 26)
por: Stange, Thoralf, et al.
Publicado: (1996)

Filamentous Hemagglutinin of Bordetella pertussis Does Not Interact with the β(2) Integrin CD11b/CD18
por: Golshani, Maryam, et al.
Publicado: (2022)

The Aminopeptidase CD13 Induces Homotypic Aggregation in Neutrophils and Impairs Collagen Invasion
por: Fiddler, Christine A., et al.
Publicado: (2016)

Inhibitory effect of anti-aminopeptidase N/CD13 antibodies on fibroblast migration
por: Lai, Amy, et al.
Publicado: (2010)

Computational study of novel natural inhibitors targeting aminopeptidase N(CD13)
por: Ge, Junliang, et al.
Publicado: (2020)

EM Structure of the Ectodomain of Integrin CD11b/CD18 and Localization of Its Ligand-Binding Site Relative to the Plasma Membrane
por: Adair, Brian D., et al.
Publicado: (2013)

Cytokine-induced respiratory burst of human neutrophils: dependence on extracellular matrix proteins and CD11/CD18 integrins
Publicado: (1989)

Platelet Glycoprotein Ibα Is a Counterreceptor for the Leukocyte Integrin Mac-1 (Cd11b/Cd18)
por: Simon, Daniel I., et al.
Publicado: (2000)

β2 Integrin CD11d/CD18: From Expression to an Emerging Role in Staged Leukocyte Migration
por: Blythe, Eoin N., et al.
Publicado: (2021)

CD11c/CD18 Dominates Adhesion of Human Monocytes, Macrophages and Dendritic Cells over CD11b/CD18
por: Sándor, Noémi, et al.
Publicado: (2016)

Localization, Shedding, Regulation and Function of Aminopeptidase N/CD13 on Fibroblast like Synoviocytes
por: Morgan, Rachel L., et al.
Publicado: (2016)

Aminopeptidase N (APN/CD13) as a target molecule for scirrhous gastric cancer
por: Nohara, Shigeo, et al.
Publicado: (2016)

Human melanoma invasion and metastasis enhancement by high expression of aminopeptidase N/CD13
por: Fujii, Hideji, et al.
Publicado: (1995)

Leishmania promastigotes require opsonic complement to bind to the human leukocyte integrin Mac-1 (CD11b/CD18)
Publicado: (1992)

Tumor necrosis factor and CD11/CD18 (beta 2) integrins act synergistically to lower cAMP in human neutrophils
Publicado: (1990)

Monocyte migration to arthritis in the rat utilizes both CD11/CD18 and very late activation antigen 4 integrin mechanisms
Publicado: (1995)

Heparin is an adhesive ligand for the leukocyte integrin Mac-1 (CD11b/CD1)
Publicado: (1995)

Expression of CD11a, CD11b, CD11c, and CD18 on Neutrophils from Different Clinical Types of Malaria in Malawian Children
por: Mandala, Wilson Lewis
Publicado: (2022)

LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18) distinctly regulate neutrophil extravasation through hotspots I and II
por: Hyun, Young-Min, et al.
Publicado: (2019)

The main neutral aminopeptidase activity of human lymphoid tumour cell lines does not originate from the aminopeptidase N-(APN; CD13) gene
por: Wex, T, et al.
Publicado: (1997)

Regulation of aminopeptidase N (EC 3.4.11.2; APN; CD13) by interferon-γ on the HL-60 cell line
por: Gabrilovac, Jelka, et al.
Publicado: (2005)

Prophylactic orthosteric inhibition of leukocyte integrin CD11b/CD18 prevents long-term fibrotic kidney failure in cynomolgus monkeys
por: Dehnadi, Abbas, et al.
Publicado: (2017)

Neutrophil Emigration in the Skin, Lungs, and Peritoneum: Different Requirements for CD11/CD18 Revealed by CD18-deficient Mice
por: Mizgerd, Joseph P., et al.
Publicado: (1997)

Aminopeptidase N (APN)/CD13 inhibitor, Ubenimex, enhances radiation sensitivity in human cervical cancer
por: Tsukamoto, Hirohisa, et al.
Publicado: (2008)

Contribution of the porcine aminopeptidase N (CD13) receptor density to porcine epidemic diarrhea virus infection
por: Nam, Eeuri, et al.
Publicado: (2010)

Expression of aminopeptidase N/CD13 in tumour-infiltrating lymphocytes from human renal cell carcinoma
por: Riemann, Dagmar, et al.
Publicado: (1994)

Design and synthesis of novel chloramphenicol amine derivatives as potent aminopeptidase N (APN/CD13) inhibitors
por: Yang, Kanghui, et al.
Publicado: (2009)

CD11c/CD18, a transmembrane signaling receptor for lipopolysaccharide
Publicado: (1995)

The Adenylate Cyclase Toxin of Bordetella pertussis Binds to Target Cells via the α(M)β(2) Integrin (Cd11b/Cd18)
por: Guermonprez, Pierre, et al.
Publicado: (2001)

The I domain is a major recognition site on the leukocyte integrin Mac- 1 (CD11b/CD18) for four distinct adhesion ligands
Publicado: (1993)

Integrin α(D)β(2) (CD11d/CD18) Is Expressed by Human Circulating and Tissue Myeloid Leukocytes and Mediates Inflammatory Signaling
por: Miyazaki, Yasunari, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_b56996noth9f61m3mm3h5jd62r