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Transcriptomic analysis reveals a tissue-specific loss of identity during ageing and cancer

INTRODUCTION: Understanding changes in cell identity in cancer and ageing is of great importance. In this work, we analyzed how gene expression changes in human tissues are associated with tissue specificity during cancer and ageing using transcriptome data from TCGA and GTEx. RESULTS: We found sign...

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Detalles Bibliográficos
Autores principales: dos Santos, Gabriel Arantes, Chatsirisupachai, Kasit, Avelar, Roberto A., de Magalhães, João Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604446/
https://www.ncbi.nlm.nih.gov/pubmed/37884865
http://dx.doi.org/10.1186/s12864-023-09756-w

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