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Transcriptomic analysis reveals a tissue-specific loss of identity during ageing and cancer
INTRODUCTION: Understanding changes in cell identity in cancer and ageing is of great importance. In this work, we analyzed how gene expression changes in human tissues are associated with tissue specificity during cancer and ageing using transcriptome data from TCGA and GTEx. RESULTS: We found sign...
Autores principales: | dos Santos, Gabriel Arantes, Chatsirisupachai, Kasit, Avelar, Roberto A., de Magalhães, João Pedro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604446/ https://www.ncbi.nlm.nih.gov/pubmed/37884865 http://dx.doi.org/10.1186/s12864-023-09756-w |
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