Hematologic Abnormalities After COVID-19 Infection: A Case of Coombs-Negative Hemolytic Anemia and Thrombocytopenia

The occurrence of hemolytic anemia in patients with active SARS-CoV-2 infection has been documented in medical literature. While relatively uncommon, there have been instances where this condition presents as a Coombs-negative hemolytic anemia. In this research study, we report a distinctive case of...

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Autores principales: Siegenthaler, Alanna Glidden, Ghelani, Ghanshyam, Brady, Amy, Loon, Taylor, Madhira, Bhaskara Reddy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604495/
https://www.ncbi.nlm.nih.gov/pubmed/37882166
http://dx.doi.org/10.1177/23247096231207687
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author Siegenthaler, Alanna Glidden
Ghelani, Ghanshyam
Brady, Amy
Loon, Taylor
Madhira, Bhaskara Reddy
author_facet Siegenthaler, Alanna Glidden
Ghelani, Ghanshyam
Brady, Amy
Loon, Taylor
Madhira, Bhaskara Reddy
author_sort Siegenthaler, Alanna Glidden
collection PubMed
description The occurrence of hemolytic anemia in patients with active SARS-CoV-2 infection has been documented in medical literature. While relatively uncommon, there have been instances where this condition presents as a Coombs-negative hemolytic anemia. In this research study, we report a distinctive case of Coombs-negative hemolytic anemia and thrombocytopenia in a patient with a known history of COVID-19 infection. The patient demonstrated a favorable response to treatment involving the administration of steroids and intravenous immunoglobulin (IVIG) therapy. This case adds to the existing body of evidence regarding the hematological manifestations of SARS-CoV-2 infection, highlighting the importance of considering and managing hematological complications in patients with COVID-19.
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spelling pubmed-106044952023-10-28 Hematologic Abnormalities After COVID-19 Infection: A Case of Coombs-Negative Hemolytic Anemia and Thrombocytopenia Siegenthaler, Alanna Glidden Ghelani, Ghanshyam Brady, Amy Loon, Taylor Madhira, Bhaskara Reddy J Investig Med High Impact Case Rep Case Report The occurrence of hemolytic anemia in patients with active SARS-CoV-2 infection has been documented in medical literature. While relatively uncommon, there have been instances where this condition presents as a Coombs-negative hemolytic anemia. In this research study, we report a distinctive case of Coombs-negative hemolytic anemia and thrombocytopenia in a patient with a known history of COVID-19 infection. The patient demonstrated a favorable response to treatment involving the administration of steroids and intravenous immunoglobulin (IVIG) therapy. This case adds to the existing body of evidence regarding the hematological manifestations of SARS-CoV-2 infection, highlighting the importance of considering and managing hematological complications in patients with COVID-19. SAGE Publications 2023-10-26 /pmc/articles/PMC10604495/ /pubmed/37882166 http://dx.doi.org/10.1177/23247096231207687 Text en © 2023 American Federation for Medical Research https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Siegenthaler, Alanna Glidden
Ghelani, Ghanshyam
Brady, Amy
Loon, Taylor
Madhira, Bhaskara Reddy
Hematologic Abnormalities After COVID-19 Infection: A Case of Coombs-Negative Hemolytic Anemia and Thrombocytopenia
title Hematologic Abnormalities After COVID-19 Infection: A Case of Coombs-Negative Hemolytic Anemia and Thrombocytopenia
title_full Hematologic Abnormalities After COVID-19 Infection: A Case of Coombs-Negative Hemolytic Anemia and Thrombocytopenia
title_fullStr Hematologic Abnormalities After COVID-19 Infection: A Case of Coombs-Negative Hemolytic Anemia and Thrombocytopenia
title_full_unstemmed Hematologic Abnormalities After COVID-19 Infection: A Case of Coombs-Negative Hemolytic Anemia and Thrombocytopenia
title_short Hematologic Abnormalities After COVID-19 Infection: A Case of Coombs-Negative Hemolytic Anemia and Thrombocytopenia
title_sort hematologic abnormalities after covid-19 infection: a case of coombs-negative hemolytic anemia and thrombocytopenia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604495/
https://www.ncbi.nlm.nih.gov/pubmed/37882166
http://dx.doi.org/10.1177/23247096231207687
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