Exploiting Differences in Heme Biosynthesis between Bacterial Species to Screen for Novel Antimicrobials

The final three steps of heme biogenesis exhibit notable differences between di- and mono-derm bacteria. The former employs the protoporphyrin-dependent (PPD) pathway, while the latter utilizes the more recently uncovered coproporphyrin-dependent (CPD) pathway. In order to devise a rapid screen for...

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Detalles Bibliográficos
Autores principales: Jackson, Laurie K., Dailey, Tammy A., Anderle, Brenden, Warren, Martin J., Bergonia, Hector A., Dailey, Harry A., Phillips, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604556/
https://www.ncbi.nlm.nih.gov/pubmed/37892169
http://dx.doi.org/10.3390/biom13101485

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604556/
https://www.ncbi.nlm.nih.gov/pubmed/37892169
http://dx.doi.org/10.3390/biom13101485

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