Pharmacological Akt and JNK Kinase Inhibitors 10-DEBC and SP600125 Potentiate Anti-Glioblastoma Effect of Menadione and Ascorbic Acid Combination in Human U251 Glioblastoma Cells

Glioblastoma multiforme (GBM) is the most lethal primary brain tumor in adults, characterized by a highly invasive nature and therapy resistance. Combination of menadione and ascorbic acid (AA+MD) exerts strong ROS-mediated anti-GBM activity in vitro. The objective of this study was to improve AA+MD...

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Detalles Bibliográficos
Autores principales: Despotović, Ana, Janjetović, Kristina, Zogović, Nevena, Tovilović-Kovačević, Gordana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604608/
https://www.ncbi.nlm.nih.gov/pubmed/37893026
http://dx.doi.org/10.3390/biomedicines11102652

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604608/
https://www.ncbi.nlm.nih.gov/pubmed/37893026
http://dx.doi.org/10.3390/biomedicines11102652

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