Development of Piperazine- and Oxazine-Linked Pyrimidines as p65 Subunit Binders of NF–κB in Human Breast Cancer Cells

Nuclear factor kappa B (NF–κB) is a potential therapeutic target in breast cancer. In the current study, a new class of oxazine– and piperazine–linked pyrimidines was developed as inhibitors of NF–κB, overcoming the complexity of the oxazine structure found in nature and enabling synthesis under lab...

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Detalles Bibliográficos
Autores principales: Ravish, Akshay, Narasimhachar, Bhanuprakash C., Xi, Zhang, Vishwanath, Divakar, Mohan, Arunkumar, Gaonkar, Santosh L., Chandrashekara, Paduvalahippe Gowdegowda, Ahn, Kwang Seok, Pandey, Vijay, Lobie, Peter E., Basappa, Basappa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604619/
https://www.ncbi.nlm.nih.gov/pubmed/37893090
http://dx.doi.org/10.3390/biomedicines11102716

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