Cargando…

The Shortening of Leukocyte Telomere Length Contributes to Alzheimer’s Disease: Further Evidence from Late-Onset Familial and Sporadic Cases

SIMPLE SUMMARY: Alzheimer’s disease (AD) is one of the most common forms of dementia in the aging population. The shortening of telomeres, which are complex structures at the ends of chromosomes, is considered one of the hallmarks of aging and has been implicated in several neurodegenerative disease...

Descripción completa

Detalles Bibliográficos
Autores principales:	Crocco, Paolina, De Rango, Francesco, Dato, Serena, La Grotta, Rossella, Maletta, Raffaele, Bruni, Amalia Cecilia, Passarino, Giuseppe, Rose, Giuseppina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604697/ https://www.ncbi.nlm.nih.gov/pubmed/37886996 http://dx.doi.org/10.3390/biology12101286

Ejemplares similares

Telomere length as a function of age at population level parallels human survival curves
por: Crocco, Paolina, et al.
Publicado: (2021)

Antioxidants and Quality of Aging: Further Evidences for a Major Role of TXNRD1 Gene Variability on Physical Performance at Old Age
por: Dato, Serena, et al.
Publicado: (2015)

Uncoupling protein 4 (UCP4) gene variability in neurodegenerative disorders: further evidence of association in Frontotemporal dementia
por: Montesanto, Alberto, et al.
Publicado: (2018)

Further Support to the Uncoupling-to-Survive Theory: The Genetic Variation of Human UCP Genes Is Associated with Longevity
por: Rose, Giuseppina, et al.
Publicado: (2011)

Physical decline and survival in the elderly are affected by the genetic variability of amino acid transporter genes
por: Crocco, Paolina, et al.
Publicado: (2018)

Inositol Polyphosphate Multikinase (IPMK), a Gene Coding for a Potential Moonlighting Protein, Contributes to Human Female Longevity
por: De Rango, Francesco, et al.
Publicado: (2019)

Exploring the Role of Genetic Variability and Lifestyle in Oxidative Stress Response for Healthy Aging and Longevity
por: Dato, Serena, et al.
Publicado: (2013)

Biomarkers of Frailty: miRNAs as Common Signatures of Impairment in Cognitive and Physical Domains
por: Dato, Serena, et al.
Publicado: (2022)

Circulating miR-181a as a novel potential plasma biomarker for multimorbidity burden in the older population
por: Iannone, Francesca, et al.
Publicado: (2022)

The mitochondrial DNA control region shows genetically correlated levels of heteroplasmy in leukocytes of centenarians and their offspring
por: Rose, Giuseppina, et al.
Publicado: (2007)

Somatic Point Mutations in mtDNA Control Region Are Influenced by Genetic Background and Associated with Healthy Aging: A GEHA Study
por: Rose, Giuseppina, et al.
Publicado: (2010)

Inter-Individual Variability in Xenobiotic-Metabolizing Enzymes: Implications for Human Aging and Longevity
por: Crocco, Paolina, et al.
Publicado: (2019)

Sex‐ and APOE‐specific genetic risk factors for late‐onset Alzheimer's disease: Evidence from gene–gene interaction of longevity‐related loci
por: Dato, Serena, et al.
Publicado: (2023)

Shortened leukocyte telomere length in young adults who use methamphetamine
por: Lin, Yen-Feng, et al.
Publicado: (2021)

Expression Patterns of Muscle-Specific miR-133b and miR-206 Correlate with Nutritional Status and Sarcopenia
por: Iannone, Francesca, et al.
Publicado: (2020)

The Genetic Variability of Members of the SLC38 Family of Amino Acid Transporters (SLC38A3, SLC38A7 and SLC38A9) Affects Susceptibility to Type 2 Diabetes and Vascular Complications
por: Crocco, Paolina, et al.
Publicado: (2022)

Telomere shortening in leukocyte subpopulations in depression
por: Karabatsiakis, Alexander, et al.
Publicado: (2014)

Significant Shortening of Leukocyte Telomere Length in Korean Patients with Bipolar Disorder 1
por: Joo, Eun-Jeong, et al.
Publicado: (2021)

Leukocyte Telomeric G-Tail Length Shortening Is Associated with Esophageal Cancer Recurrence
por: Han, Jiayan, et al.
Publicado: (2022)

Correlates of telomere length shortening in peripheral leukocytes of HIV-infected individuals and association with leukoaraiosis
por: Minami, Rumi, et al.
Publicado: (2019)

Longitudinal versus Cross-sectional Evaluations of Leukocyte Telomere Length Dynamics: Age-Dependent Telomere Shortening is the Rule
por: Chen, W., et al.
Publicado: (2011)

Correction: Syndecan-4 as a genetic determinant of the metabolic syndrome
por: Crocco, Paolina, et al.
Publicado: (2023)

Syndecan-4 as a genetic determinant of the metabolic syndrome
por: Crocco, Paolina, et al.
Publicado: (2023)

Shortened leukocyte telomere length in type 2 diabetes mellitus: genetic polymorphisms in mitochondrial uncoupling proteins and telomeric pathways
por: Zhou, Yuling, et al.
Publicado: (2016)

Oxidative Stress-induced Telomere Length Shortening of Circulating Leukocyte in Patients with Obstructive Sleep Apnea
por: Kim, Kyung Soo, et al.
Publicado: (2016)

Obesity Accelerates Leukocyte Telomere Length Shortening in Apparently Healthy Adults: A Meta-Analysis
por: Khosravaniardakani, Sheida, et al.
Publicado: (2022)

Bitter Taste Receptor Polymorphisms and Human Aging
por: Campa, Daniele, et al.
Publicado: (2012)

Functional Haplotypes of the hTERT Gene, Leukocyte Telomere Length Shortening, and the Risk of Peripheral Arterial Disease
por: Zhang, Weili, et al.
Publicado: (2012)

The shortening of leukocyte telomere length relates to DNA hypermethylation of LINE-1 in type 2 diabetes mellitus
por: Wu, Yue, et al.
Publicado: (2017)

Leukocyte Telomere Length Shortening, hTERT Genetic Polymorphisms and Risk of Childhood Acute Lymphoblastic Leukemia
por: Eskandari, Ebrahim, et al.
Publicado: (2018)

Omics in a Digital World: The Role of Bioinformatics in Providing New Insights Into Human Aging
por: Dato, Serena, et al.
Publicado: (2021)

Asynchronous Shortening of Telomere Length and Cardiovascular Outcomes
por: Wang, Chao-Yung
Publicado: (2018)

The genetic component of human longevity: New insights from the analysis of pathway‐based SNP‐SNP interactions
por: Dato, Serena, et al.
Publicado: (2018)

Telomere shortening and telomere position effect in mild ring 17 syndrome
por: Surace, Cecilia, et al.
Publicado: (2014)

Characteristics of salivary telomere length shortening in preterm infants
por: Schneper, Lisa M., et al.
Publicado: (2023)

Alcohol consumption and leukocyte telomere length
por: Dixit, Shalini, et al.
Publicado: (2019)

Telomere Shortening in Blood Leukocytes of Patients with Chronic Obstructive Pulmonary Disease
por: Sadr, Makan, et al.
Publicado: (2015)

High heritability of telomere length and low heritability of telomere shortening in wild birds
por: Bauch, Christina, et al.
Publicado: (2021)

Leukocyte Telomere Length Shortening Implies Plaque Instability and Major Adverse Cardiovascular Events in Patients With Angiographically Intermediate Lesions
por: Zhang, Alian, et al.
Publicado: (2022)

Shortened Leukocyte Telomere Length Is Associated With Glycemic Progression in Type 2 Diabetes: A Prospective and Mendelian Randomization Analysis
por: Cheng, Feifei, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_r84lndaq9cmbjj6f84s8cacp7n