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Effect of Probiotic Therapy on Neuropsychiatric Manifestations in Children with Multiple Neurotransmitter Disorders: A Study

Probiotics, also known as psychobiotics, have been linked to cognitive functions, memory, learning, and behavior, in addition to their positive effects on the digestive tract. The purpose of this study is to examine the psychoemotional effects and cognitive functioning in children with gastrointesti...

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Autores principales: Matiș, Loredana, Alexandru, Bogdana Ariana, Fodor, Radu, Daina, Lucia Georgeta, Ghitea, Timea Claudia, Vlad, Silviu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604742/
https://www.ncbi.nlm.nih.gov/pubmed/37893017
http://dx.doi.org/10.3390/biomedicines11102643
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author Matiș, Loredana
Alexandru, Bogdana Ariana
Fodor, Radu
Daina, Lucia Georgeta
Ghitea, Timea Claudia
Vlad, Silviu
author_facet Matiș, Loredana
Alexandru, Bogdana Ariana
Fodor, Radu
Daina, Lucia Georgeta
Ghitea, Timea Claudia
Vlad, Silviu
author_sort Matiș, Loredana
collection PubMed
description Probiotics, also known as psychobiotics, have been linked to cognitive functions, memory, learning, and behavior, in addition to their positive effects on the digestive tract. The purpose of this study is to examine the psychoemotional effects and cognitive functioning in children with gastrointestinal disorders who undergo psychobiotherapy. A total of 135 participants, aged 5–18 years, were divided into three groups based on the pediatrician’s diagnosis: Group I (Control) consisted of 37 patients (27.4%), Group II included 65 patients (48.1%) with psychoanxiety disorders, and Group III comprised 33 individuals (24.4%) with psychiatric disorders. The study monitored neurotransmitter levels such as serotonin, GABA, glutamate, cortisol, and DHEA, as well as neuropsychiatric symptoms including headaches, fatigue, mood swings, hyperactivity, aggressiveness, sleep disorders, and lack of concentration in patients who had gastrointestinal issues such as constipation, diarrhea, and other gastrointestinal problems. The results indicate that psychobiotics have a significant impact on reducing hyperactivity and aggression, and improving concentration. While further extensive studies are needed, these findings offer promising insights into the complexity of a child’s neuropsychic behavior and the potential for balancing certain behaviors through psychobiotics.
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spelling pubmed-106047422023-10-28 Effect of Probiotic Therapy on Neuropsychiatric Manifestations in Children with Multiple Neurotransmitter Disorders: A Study Matiș, Loredana Alexandru, Bogdana Ariana Fodor, Radu Daina, Lucia Georgeta Ghitea, Timea Claudia Vlad, Silviu Biomedicines Article Probiotics, also known as psychobiotics, have been linked to cognitive functions, memory, learning, and behavior, in addition to their positive effects on the digestive tract. The purpose of this study is to examine the psychoemotional effects and cognitive functioning in children with gastrointestinal disorders who undergo psychobiotherapy. A total of 135 participants, aged 5–18 years, were divided into three groups based on the pediatrician’s diagnosis: Group I (Control) consisted of 37 patients (27.4%), Group II included 65 patients (48.1%) with psychoanxiety disorders, and Group III comprised 33 individuals (24.4%) with psychiatric disorders. The study monitored neurotransmitter levels such as serotonin, GABA, glutamate, cortisol, and DHEA, as well as neuropsychiatric symptoms including headaches, fatigue, mood swings, hyperactivity, aggressiveness, sleep disorders, and lack of concentration in patients who had gastrointestinal issues such as constipation, diarrhea, and other gastrointestinal problems. The results indicate that psychobiotics have a significant impact on reducing hyperactivity and aggression, and improving concentration. While further extensive studies are needed, these findings offer promising insights into the complexity of a child’s neuropsychic behavior and the potential for balancing certain behaviors through psychobiotics. MDPI 2023-09-26 /pmc/articles/PMC10604742/ /pubmed/37893017 http://dx.doi.org/10.3390/biomedicines11102643 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Matiș, Loredana
Alexandru, Bogdana Ariana
Fodor, Radu
Daina, Lucia Georgeta
Ghitea, Timea Claudia
Vlad, Silviu
Effect of Probiotic Therapy on Neuropsychiatric Manifestations in Children with Multiple Neurotransmitter Disorders: A Study
title Effect of Probiotic Therapy on Neuropsychiatric Manifestations in Children with Multiple Neurotransmitter Disorders: A Study
title_full Effect of Probiotic Therapy on Neuropsychiatric Manifestations in Children with Multiple Neurotransmitter Disorders: A Study
title_fullStr Effect of Probiotic Therapy on Neuropsychiatric Manifestations in Children with Multiple Neurotransmitter Disorders: A Study
title_full_unstemmed Effect of Probiotic Therapy on Neuropsychiatric Manifestations in Children with Multiple Neurotransmitter Disorders: A Study
title_short Effect of Probiotic Therapy on Neuropsychiatric Manifestations in Children with Multiple Neurotransmitter Disorders: A Study
title_sort effect of probiotic therapy on neuropsychiatric manifestations in children with multiple neurotransmitter disorders: a study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604742/
https://www.ncbi.nlm.nih.gov/pubmed/37893017
http://dx.doi.org/10.3390/biomedicines11102643
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