Cargando…
Integrative Approaches in Acute Ischemic Stroke: From Symptom Recognition to Future Innovations
Among the high prevalence of cerebrovascular diseases nowadays, acute ischemic stroke stands out, representing a significant worldwide health issue with important socio-economic implications. Prompt diagnosis and intervention are important milestones for the management of this multifaceted pathology...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604797/ https://www.ncbi.nlm.nih.gov/pubmed/37892991 http://dx.doi.org/10.3390/biomedicines11102617 |
_version_ | 1785126921147777024 |
---|---|
author | Saceleanu, Vicentiu Mircea Toader, Corneliu Ples, Horia Covache-Busuioc, Razvan-Adrian Costin, Horia Petre Bratu, Bogdan-Gabriel Dumitrascu, David-Ioan Bordeianu, Andrei Corlatescu, Antonio Daniel Ciurea, Alexandru Vlad |
author_facet | Saceleanu, Vicentiu Mircea Toader, Corneliu Ples, Horia Covache-Busuioc, Razvan-Adrian Costin, Horia Petre Bratu, Bogdan-Gabriel Dumitrascu, David-Ioan Bordeianu, Andrei Corlatescu, Antonio Daniel Ciurea, Alexandru Vlad |
author_sort | Saceleanu, Vicentiu Mircea |
collection | PubMed |
description | Among the high prevalence of cerebrovascular diseases nowadays, acute ischemic stroke stands out, representing a significant worldwide health issue with important socio-economic implications. Prompt diagnosis and intervention are important milestones for the management of this multifaceted pathology, making understanding the various stroke-onset symptoms crucial. A key role in acute ischemic stroke management is emphasizing the essential role of a multi-disciplinary team, therefore, increasing the efficiency of recognition and treatment. Neuroimaging and neuroradiology have evolved dramatically over the years, with multiple approaches that provide a higher understanding of the morphological aspects as well as timely recognition of cerebral artery occlusions for effective therapy planning. Regarding the treatment matter, the pharmacological approach, particularly fibrinolytic therapy, has its merits and challenges. Endovascular thrombectomy, a game-changer in stroke management, has witnessed significant advances, with technologies like stent retrievers and aspiration catheters playing pivotal roles. For select patients, combining pharmacological and endovascular strategies offers evidence-backed benefits. The aim of our comprehensive study on acute ischemic stroke is to efficiently compare the current therapies, recognize novel possibilities from the literature, and describe the state of the art in the interdisciplinary approach to acute ischemic stroke. As we aspire for holistic patient management, the emphasis is not just on medical intervention but also on physical therapy, mental health, and community engagement. The future holds promising innovations, with artificial intelligence poised to reshape stroke diagnostics and treatments. Bridging the gap between groundbreaking research and clinical practice remains a challenge, urging continuous collaboration and research. |
format | Online Article Text |
id | pubmed-10604797 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-106047972023-10-28 Integrative Approaches in Acute Ischemic Stroke: From Symptom Recognition to Future Innovations Saceleanu, Vicentiu Mircea Toader, Corneliu Ples, Horia Covache-Busuioc, Razvan-Adrian Costin, Horia Petre Bratu, Bogdan-Gabriel Dumitrascu, David-Ioan Bordeianu, Andrei Corlatescu, Antonio Daniel Ciurea, Alexandru Vlad Biomedicines Review Among the high prevalence of cerebrovascular diseases nowadays, acute ischemic stroke stands out, representing a significant worldwide health issue with important socio-economic implications. Prompt diagnosis and intervention are important milestones for the management of this multifaceted pathology, making understanding the various stroke-onset symptoms crucial. A key role in acute ischemic stroke management is emphasizing the essential role of a multi-disciplinary team, therefore, increasing the efficiency of recognition and treatment. Neuroimaging and neuroradiology have evolved dramatically over the years, with multiple approaches that provide a higher understanding of the morphological aspects as well as timely recognition of cerebral artery occlusions for effective therapy planning. Regarding the treatment matter, the pharmacological approach, particularly fibrinolytic therapy, has its merits and challenges. Endovascular thrombectomy, a game-changer in stroke management, has witnessed significant advances, with technologies like stent retrievers and aspiration catheters playing pivotal roles. For select patients, combining pharmacological and endovascular strategies offers evidence-backed benefits. The aim of our comprehensive study on acute ischemic stroke is to efficiently compare the current therapies, recognize novel possibilities from the literature, and describe the state of the art in the interdisciplinary approach to acute ischemic stroke. As we aspire for holistic patient management, the emphasis is not just on medical intervention but also on physical therapy, mental health, and community engagement. The future holds promising innovations, with artificial intelligence poised to reshape stroke diagnostics and treatments. Bridging the gap between groundbreaking research and clinical practice remains a challenge, urging continuous collaboration and research. MDPI 2023-09-23 /pmc/articles/PMC10604797/ /pubmed/37892991 http://dx.doi.org/10.3390/biomedicines11102617 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Saceleanu, Vicentiu Mircea Toader, Corneliu Ples, Horia Covache-Busuioc, Razvan-Adrian Costin, Horia Petre Bratu, Bogdan-Gabriel Dumitrascu, David-Ioan Bordeianu, Andrei Corlatescu, Antonio Daniel Ciurea, Alexandru Vlad Integrative Approaches in Acute Ischemic Stroke: From Symptom Recognition to Future Innovations |
title | Integrative Approaches in Acute Ischemic Stroke: From Symptom Recognition to Future Innovations |
title_full | Integrative Approaches in Acute Ischemic Stroke: From Symptom Recognition to Future Innovations |
title_fullStr | Integrative Approaches in Acute Ischemic Stroke: From Symptom Recognition to Future Innovations |
title_full_unstemmed | Integrative Approaches in Acute Ischemic Stroke: From Symptom Recognition to Future Innovations |
title_short | Integrative Approaches in Acute Ischemic Stroke: From Symptom Recognition to Future Innovations |
title_sort | integrative approaches in acute ischemic stroke: from symptom recognition to future innovations |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604797/ https://www.ncbi.nlm.nih.gov/pubmed/37892991 http://dx.doi.org/10.3390/biomedicines11102617 |
work_keys_str_mv | AT saceleanuvicentiumircea integrativeapproachesinacuteischemicstrokefromsymptomrecognitiontofutureinnovations AT toadercorneliu integrativeapproachesinacuteischemicstrokefromsymptomrecognitiontofutureinnovations AT pleshoria integrativeapproachesinacuteischemicstrokefromsymptomrecognitiontofutureinnovations AT covachebusuiocrazvanadrian integrativeapproachesinacuteischemicstrokefromsymptomrecognitiontofutureinnovations AT costinhoriapetre integrativeapproachesinacuteischemicstrokefromsymptomrecognitiontofutureinnovations AT bratubogdangabriel integrativeapproachesinacuteischemicstrokefromsymptomrecognitiontofutureinnovations AT dumitrascudavidioan integrativeapproachesinacuteischemicstrokefromsymptomrecognitiontofutureinnovations AT bordeianuandrei integrativeapproachesinacuteischemicstrokefromsymptomrecognitiontofutureinnovations AT corlatescuantoniodaniel integrativeapproachesinacuteischemicstrokefromsymptomrecognitiontofutureinnovations AT ciureaalexandruvlad integrativeapproachesinacuteischemicstrokefromsymptomrecognitiontofutureinnovations |