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Oct4 and Hypoxia Dual-Regulated Oncolytic Adenovirus Armed with shRNA-Targeting Dendritic Cell Immunoreceptor Exerts Potent Antitumor Activity against Bladder Cancer

Immunotherapy has emerged as a promising modality for cancer treatment. Dendritic cell immunoreceptor (DCIR), a C-type lectin receptor, is expressed mainly by dendritic cells (DCs) and mediates inhibitory intracellular signaling. Inhibition of DCIR activation may enhance antitumor activity. DCIR is...

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Detalles Bibliográficos
Autores principales: Hu, Che-Yuan, Hung, Chi-Feng, Chen, Pi-Che, Hsu, Jia-Yu, Wang, Chung-Teng, Lai, Ming-Derg, Tsai, Yuh-Shyan, Shiau, Ai-Li, Shieh, Gia-Shing, Wu, Chao-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604824/
https://www.ncbi.nlm.nih.gov/pubmed/37892972
http://dx.doi.org/10.3390/biomedicines11102598