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In Vivo Ultrafast Doppler Imaging Combined with Confocal Microscopy and Behavioral Approaches to Gain Insight into the Central Expression of Peripheral Neuropathy in Trembler-J Mice

SIMPLE SUMMARY: In this work, we explore the central compromise in TrJ/+ mice, a model for the peripheral neuropathy Charcot-Marie-Tooth, using three different approximations: Ultrafast Doppler, Confocal Microscopy, and behavioral tests, exposing alterations in the brain vasculature, as well as an a...

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Detalles Bibliográficos
Autores principales: Martínez Barreiro, Mariana, Vázquez Alberdi, Lucia, De León, Lucila, Avellanal, Guadalupe, Duarte, Andrea, Anzibar Fialho, Maximiliano, Baranger, Jérôme, Calero, Miguel, Rubido, Nicolás, Tanter, Mickael, Negreira, Carlos, Brum, Javier, Damián, Juan Pablo, Kun, Alejandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604841/
https://www.ncbi.nlm.nih.gov/pubmed/37887034
http://dx.doi.org/10.3390/biology12101324