Cargando…

Progesterone Receptor Membrane Component 1 (PGRMC1) Modulates Tumour Progression, the Immune Microenvironment and the Response to Therapy in Glioblastoma

Progesterone Receptor Membrane Component 1 (PGRMC1) is a tumour-promoting factor in several types of cancer but its role in brain tumours is poorly characterized thus far. Our study aimed to determine the effect of PGRMC1 on glioblastoma (GBM) pathophysiology using two independent cohorts of IDH wil...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dumitru, Claudia Alexandra, Schröder, Hannah, Schäfer, Frederik Till Alexander, Aust, Jan Friedrich, Kreße, Nina, Siebert, Carl Ludwig Raven, Stein, Klaus-Peter, Haghikia, Aiden, Wilkens, Ludwig, Mawrin, Christian, Sandalcioglu, Ibrahim Erol
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604944/ https://www.ncbi.nlm.nih.gov/pubmed/37887342 http://dx.doi.org/10.3390/cells12202498

Ejemplares similares

PLOD2 Is a Prognostic Marker in Glioblastoma That Modulates the Immune Microenvironment and Tumor Progression
por: Kreße, Nina, et al.
Publicado: (2022)

Brain biopsy in patients with CLIPPERS syndrome: why and when
por: Galazky, Imke, et al.
Publicado: (2022)

Progesterone Receptor Membrane Component (PGRMC)1 and PGRMC2 and Their Roles in Ovarian and Endometrial Cancer
por: Peluso, John J., et al.
Publicado: (2021)

Extravascular optical coherence tomography of cerebral vessel walls in vivo
por: Hartmann, Karl, et al.
Publicado: (2023)

Is the central nervous system enclosed by a mesothel?
por: Hartmann, Karl, et al.
Publicado: (2023)

Dynein Light Chain Protein Tctex1: A Novel Prognostic Marker and Molecular Mediator in Glioblastoma
por: Dumitru, Claudia Alexandra, et al.
Publicado: (2021)

PGRMC1 and PGRMC2 in uterine physiology and disease
por: Pru, James K., et al.
Publicado: (2013)

Sex-specific clinicopathological significance of novel (Frizzled-7) and established (MGMT, IDH1) biomarkers in glioblastoma
por: Schiffgens, Salveena, et al.
Publicado: (2016)

Identification of the Sigma-2 Receptor: Distinct from the Progesterone Receptor Membrane Component 1 (PGRMC1)
por: Hiranita, Takato
Publicado: (2016)

PGRMC Proteins Are Coming of Age: A Special Issue on the Role of PGRMC1 and PGRMC2 in Metabolism and Cancer Biology
por: Cahill, Michael A., et al.
Publicado: (2021)

New Insights on the Progesterone (P4) and PGRMC1/NENF Complex Interactions in Colorectal Cancer Progression
por: Kamińska, Joanna, et al.
Publicado: (2023)

Pgrmc1: new roles in the microglial mediation of progesterone-antagonism of estradiol-dependent neurite sprouting and in microglial activation
por: Bali, N., et al.
Publicado: (2013)

Progesterone Can Directly Inhibit the Life Activities of Toxoplasma gondii In Vitro through the Progesterone Receptor Membrane Component (PGRMC)
por: Wu, Yihan, et al.
Publicado: (2022)

Epitope mapping of anti-PGRMC1 antibodies reveals the non-conventional membrane topology of PGRMC1 on the cell surface
por: Kim, Ji Yea, et al.
Publicado: (2019)

Progesterone receptor membrane component 1 (PGRMC1) binds and stabilizes cytochromes P450 through a heme-independent mechanism
por: McGuire, Meredith R., et al.
Publicado: (2021)

PGRMC1 Inhibits Progesterone-Evoked Proliferation and Ca(2+) Entry Via STIM2 in MDA-MB-231 Cells
por: Cantonero, Carlos, et al.
Publicado: (2020)

Cloning, mapping and molecular characterization of porcine progesterone receptor membrane component 2 (PGRMC2) gene
por: Chen, Congying, et al.
Publicado: (2010)

Cannabinoids in Glioblastoma Therapy: New Applications for Old Drugs
por: Dumitru, Claudia A., et al.
Publicado: (2018)

Pgrmc1 Knockout Impairs Oocyte Maturation in Zebrafish
por: Wu, Xin-Jun, et al.
Publicado: (2018)

Insights on the Role of PGRMC1 in Mitotic and Meiotic Cell Division
por: Lodde, Valentina, et al.
Publicado: (2022)

A novel progesterone receptor membrane component (PGRMC) in the human and swine parasite Taenia solium: implications to the host-parasite relationship
por: Aguilar-Díaz, Hugo, et al.
Publicado: (2018)

PGRMC1: a new biomarker for the estrogen receptor in breast cancer
por: Craven, Rolf J
Publicado: (2008)

Comprehensive Analysis of the Implication of PGRMC1 in Triple-Negative Breast Cancer
por: Xu, Xin, et al.
Publicado: (2021)

The PGRMC1 Antagonist AG-205 Inhibits Synthesis of Galactosylceramide and Sulfatide
por: Wang-Eckhardt, Lihua, et al.
Publicado: (2021)

Molecular Docking and In Silico Simulation of Trichinella spiralis Membrane-Associated Progesterone Receptor Component 2 (Ts-MAPRC2) and Its Interaction with Human PGRMC1
por: Aleem, Muhammad Tahir, et al.
Publicado: (2022)

Down-regulation of progesterone receptor membrane component 1 (PGRMC1) in peripheral nucleated blood cells associated with premature ovarian failure (POF) and polycystic ovary syndrome (PCOS)
por: Schuster, Jens, et al.
Publicado: (2010)

PGRMC1 regulation by phosphorylation: potential new insights in controlling biological activity!
por: Cahill, Michael A., et al.
Publicado: (2016)

PGRMC1 Elevation in Multiple Cancers and Essential Role in Stem Cell Survival
por: Hampton, Kaia K., et al.
Publicado: (2016)

Data on RT-qPCR assay of nuclear progesterone receptors (nPR), membrane progesterone receptors (mPR) and progesterone receptor membrane components (PGRMC) from human uterine endometrial tissue and cancer cells of the Uterine Cervix
por: Smaglyukova, Natalia, et al.
Publicado: (2020)

Ultrasound-triggered microbubble destruction enhances the radiosensitivity of glioblastoma by inhibiting PGRMC1-mediated autophagy in vitro and in vivo
por: He, Ying, et al.
Publicado: (2022)

PARP-1 deregulation in multiple sclerosis
por: Meira, Maria, et al.
Publicado: (2019)

Identification of the PGRMC1 protein complex as the putative sigma-2 receptor binding site
por: Xu, Jinbin, et al.
Publicado: (2011)

Function and structural regulation of the carbon monoxide (CO)-responsive membrane protein PGRMC1
por: Kabe, Yasuaki, et al.
Publicado: (2018)

PGRMC1 Exerts Its Function of Anti-Influenza Virus in the Central Nervous System
por: Huang, Kun, et al.
Publicado: (2021)

PGRMC1-dependent lipophagy promotes ferroptosis in paclitaxel-tolerant persister cancer cells
por: You, Ji Hyeon, et al.
Publicado: (2021)

Clozapine Induced Disturbances in Hepatic Glucose Metabolism: The Potential Role of PGRMC1 Signaling
por: Cao, Ting, et al.
Publicado: (2021)

Expression of Progesterone Receptor Membrane Component 1 (PGRMC1), Progestin and AdipoQ Receptor 7 (PAQPR7), and Plasminogen Activator Inhibitor 1 RNA-Binding Protein (PAIRBP1) in Glioma Spheroids In Vitro
por: Hlavaty, Juraj, et al.
Publicado: (2016)

PGRMC2 is an Intracellular Heme Chaperone Critical for Adipocyte Function
por: Galmozzi, Andrea, et al.
Publicado: (2019)

Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance
por: Kabe, Yasuaki, et al.
Publicado: (2016)

TMEM97 and PGRMC1 do not mediate sigma-2 ligand-induced cell death
por: Zeng, Chenbo, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_mh54lj51mq2s5h76s1qksr338o