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Next-Generation Sequencing Analysis of Mutations in Circulating Tumor DNA from the Plasma of Patients with Head–Neck Cancer Undergoing Chemo-Radiotherapy Using a Pan-Cancer Cell-Free Assay

Using next-generation sequencing (NGS), we investigated DNA mutations in the plasma tumor cell-free circulating DNA (ctDNA) of 38 patients with inoperable squamous cell head neck cancer (SCHNC) before and after the completion of chemoradiotherapy (CRT). Baseline mutations of the TP53 were recorded i...

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Detalles Bibliográficos
Autores principales: Koukourakis, Michael I., Xanthopoulou, Erasmia, Koukourakis, Ioannis M., Fortis, Sotirios P., Kesesidis, Nikolaos, Kakouratos, Christos, Karakasiliotis, Ioannis, Baxevanis, Constantin N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604986/
https://www.ncbi.nlm.nih.gov/pubmed/37887543
http://dx.doi.org/10.3390/curroncol30100643