Characterization and Investigation of Novel Benzodioxol Derivatives as Antidiabetic Agents: An In Vitro and In Vivo Study in an Animal Model

In this study, we synthesized benzodioxol carboxamide derivatives and investigated their antidiabetic potential. The synthesized compounds (Ia-Ic and IIa-IId) underwent characterization via HRMS, (1)H-, (13)CAPT-NMR, and MicroED. Their efficacy against α-amylase was assessed in vitro, while MTS assa...

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Detalles Bibliográficos
Autores principales: Hawash, Mohammed, Al-Smadi, Derar, Kumar, Anil, Olech, Barbara, Dominiak, Paulina Maria, Jaradat, Nidal, Antari, Sarah, Mohammed, Sarah, Nasasrh, Ala’a, Abualhasan, Murad, Musa, Ahmed, Suboh, Shorooq, Çapan, İrfan, Qneibi, Mohammad, Natsheh, Hiba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604990/
https://www.ncbi.nlm.nih.gov/pubmed/37892167
http://dx.doi.org/10.3390/biom13101486

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