Cargando…

Haematological and biochemical analysis of blood samples from early and late stage breast cancer patients in India

Breast cancer is the most prevalent cancer with the maximum number of cases worldwide. Early diagnosis of the cancer is necessary for an effective treatment plan. Due to a lack of awareness, diagnosis of breast cancer at an early stage is difficult. The present study aims to evaluate and compare the...

Descripción completa

Detalles Bibliográficos
Autores principales: Shreya, Smriti, Shekher, Anusmita, Puneet, Puneet, Prasad, Shyam Babu, Prakash Jain, Buddhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605084/
https://www.ncbi.nlm.nih.gov/pubmed/37901291
http://dx.doi.org/10.6026/97320630019806
_version_ 1785126988831260672
author Shreya, Smriti
Shekher, Anusmita
Puneet, Puneet
Prasad, Shyam Babu
Prakash Jain, Buddhi
author_facet Shreya, Smriti
Shekher, Anusmita
Puneet, Puneet
Prasad, Shyam Babu
Prakash Jain, Buddhi
author_sort Shreya, Smriti
collection PubMed
description Breast cancer is the most prevalent cancer with the maximum number of cases worldwide. Early diagnosis of the cancer is necessary for an effective treatment plan. Due to a lack of awareness, diagnosis of breast cancer at an early stage is difficult. The present study aims to evaluate and compare the haematological and biochemical profiles of the early and late-stage breast cancer patient's data records. A retrospective cohort study was conducted on 56 breast cancer patients at the Institute of Medical Sciences, Banaras Hindu University India. Patient data records were obtained and haematological and biochemical parameters were arranged on an Excel sheet and analyzed. Random blood sugar (RBS), alkaline phosphates (ALP) levels, and urea levels were significantly high in patients with late-stage breast cancer (Tumor stage III and IV). At the advanced stage of breast cancer hemoglobin level falls and patients became anemic. Further large-scale studies with a greater number of patient data can help establish these parameters individually or in combination as prognostic and diagnostic markers in breast cancer staging.
format Online
Article
Text
id pubmed-10605084
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Biomedical Informatics
record_format MEDLINE/PubMed
spelling pubmed-106050842023-10-28 Haematological and biochemical analysis of blood samples from early and late stage breast cancer patients in India Shreya, Smriti Shekher, Anusmita Puneet, Puneet Prasad, Shyam Babu Prakash Jain, Buddhi Bioinformation Research Article Breast cancer is the most prevalent cancer with the maximum number of cases worldwide. Early diagnosis of the cancer is necessary for an effective treatment plan. Due to a lack of awareness, diagnosis of breast cancer at an early stage is difficult. The present study aims to evaluate and compare the haematological and biochemical profiles of the early and late-stage breast cancer patient's data records. A retrospective cohort study was conducted on 56 breast cancer patients at the Institute of Medical Sciences, Banaras Hindu University India. Patient data records were obtained and haematological and biochemical parameters were arranged on an Excel sheet and analyzed. Random blood sugar (RBS), alkaline phosphates (ALP) levels, and urea levels were significantly high in patients with late-stage breast cancer (Tumor stage III and IV). At the advanced stage of breast cancer hemoglobin level falls and patients became anemic. Further large-scale studies with a greater number of patient data can help establish these parameters individually or in combination as prognostic and diagnostic markers in breast cancer staging. Biomedical Informatics 2023-07-31 /pmc/articles/PMC10605084/ /pubmed/37901291 http://dx.doi.org/10.6026/97320630019806 Text en © 2023 Biomedical Informatics https://creativecommons.org/licenses/by/3.0/This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
spellingShingle Research Article
Shreya, Smriti
Shekher, Anusmita
Puneet, Puneet
Prasad, Shyam Babu
Prakash Jain, Buddhi
Haematological and biochemical analysis of blood samples from early and late stage breast cancer patients in India
title Haematological and biochemical analysis of blood samples from early and late stage breast cancer patients in India
title_full Haematological and biochemical analysis of blood samples from early and late stage breast cancer patients in India
title_fullStr Haematological and biochemical analysis of blood samples from early and late stage breast cancer patients in India
title_full_unstemmed Haematological and biochemical analysis of blood samples from early and late stage breast cancer patients in India
title_short Haematological and biochemical analysis of blood samples from early and late stage breast cancer patients in India
title_sort haematological and biochemical analysis of blood samples from early and late stage breast cancer patients in india
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605084/
https://www.ncbi.nlm.nih.gov/pubmed/37901291
http://dx.doi.org/10.6026/97320630019806
work_keys_str_mv AT shreyasmriti haematologicalandbiochemicalanalysisofbloodsamplesfromearlyandlatestagebreastcancerpatientsinindia
AT shekheranusmita haematologicalandbiochemicalanalysisofbloodsamplesfromearlyandlatestagebreastcancerpatientsinindia
AT puneetpuneet haematologicalandbiochemicalanalysisofbloodsamplesfromearlyandlatestagebreastcancerpatientsinindia
AT prasadshyambabu haematologicalandbiochemicalanalysisofbloodsamplesfromearlyandlatestagebreastcancerpatientsinindia
AT prakashjainbuddhi haematologicalandbiochemicalanalysisofbloodsamplesfromearlyandlatestagebreastcancerpatientsinindia