Untargeted Lipidomic Approach for Studying Different Nervous System Tissues of the Murine Model of Krabbe Disease

Krabbe disease is a rare neurodegenerative disease with an autosomal recessive character caused by a mutation in the GALC gene. The mutation leads to an accumulation of psychosine and a subsequent degeneration of oligodendrocytes and Schwann cells. Psychosine is the main biomarker of the disease. Th...

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Detalles Bibliográficos
Autores principales: Alabed, Husam B. R., Del Grosso, Ambra, Bellani, Valeria, Urbanelli, Lorena, Carpi, Sara, De Sarlo, Miriam, Bertocci, Lorenzo, Colagiorgio, Laura, Buratta, Sandra, Scaccini, Luca, Frongia Mancini, Dorotea, Tonazzini, Ilaria, Cecchini, Marco, Emiliani, Carla, Pellegrino, Roberto Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605133/
https://www.ncbi.nlm.nih.gov/pubmed/37892244
http://dx.doi.org/10.3390/biom13101562

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